Evidence map›Paper›PMID 15944531›Full record

Trial reportJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Relationship of transient ischemic dilation in dipyridamole myocardial perfusion imaging and stress-induced changes of functional parameters evaluated by Tl-201 gated SPECT.

Guang-Uei Hung, Kung-Wei Lee, Ching-Pei Chen, Wan-Yu Lin, Kuang-Tao Yang

Abstract readClinical TrialControlled Clinical Trial
PubMed Publisher
In one paragraph

Trial report in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 66 citations in OpenAlex.

  1. Transient ischemic dilation for coronary artery disease in quantitative analysis of same-day sestamibi myocardial perfusion SPECT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2012
    Trial
  2. Transient ischemic dilation ratio by [The international journal of cardiovascular imaging · 2025
    Article
  3. Article
  4. Article
  5. How variable are the volumetric measurements from gated perfusion SPECT when a one-day stress-rest protocol is used?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019
    Article
  6. Article
  7. Myocardial CT perfusion imaging for ischemia detection.Cardiovascular diagnosis and therapy · 2017
    Review
  8. Contemporary relevance of TID: Based on the company it keeps.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2015
    Article
  9. Relation of early post-stress left ventricular dyssynchrony and the extent of angiographic coronary artery disease.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2014
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Transient ischemic dilation in SPECT myocardial perfusion imaging for prediction of severe coronary artery disease in diabetic patients.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2013
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. The significance of transient ischemic dilation in the setting of otherwise normal SPECT radionuclide myocardial perfusion images.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2011
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Guang-Uei HungDepartment of Nuclear Medicine, Changhua Christian Hospital, Taiwan.
Kung-Wei Lee
Ching-Pei Chen
Wan-Yu Lin
Kuang-Tao Yang
Changhua Christian Hospital · TWTaichung Veterans General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study assessed whether transient ischemic dilation (TID) of the left ventricle is related to ischemic stunning, manifested by stress-induced decrease of left ventricular ejection fraction (LVEF) and worsening of wall motion, by use of dipyridamole-stress and redistribution thallium 201 gated single photon emission computed tomography (SPECT). METHODS AND

resultsNinety-two consecutive patients undergoing dipyridamole Tl-201 gated SPECT were included. Patients with a TID ratio in the highest quartile were defined as having TID. In patients with TID, end-diastolic volume (EDV) and end-systolic volume (ESV) were both significantly greater on dipyridamole-stress images than on redistribution images (P < .001). The degree of enlargement was much greater for ESV than EDV. In patients without TID, EDV and ESV were both decreased after stress (P < .001). Patients with TID had a lower mean LVEF on dipyridamole-stress images than on redistribution images (P < .001). Patients without TID had a higher mean LVEF on dipyridamole-stress images than on redistribution images (P < .001). Patients with TID had a significant worsening of global wall motion on dipyridamole-stress images than on redistribution images (P < .001), but patients without TID did not.

conclusionTID was significantly correlated with ischemic stunning, and the enlargement of ESV was an important factor resulting in TID.

Indexed as

DipyridamoleThalliumAgedCoronary Artery DiseaseExercise TestFemaleGated Blood-Pool ImagingHumansImage EnhancementImage Interpretation, Computer-AssistedMaleMyocardial IschemiaMyocardial StunningPrognosisRadiopharmaceuticalsReproducibility of ResultsDipyridamoleRadiopharmaceuticalsThalliumthallium chlorideVasodilator Agents

Identifiers

PMID15944531
OpenAlexW2042488338

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.