ArticlePediatric nephrology (Berlin, Germany)2005
Epidemiology treatment and outcome of childhood systemic lupus erythematosus in Egypt.
Article in Pediatric nephrology (Berlin, Germany), 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Management and outcomes in children with lupus nephritis in the developing countries.Pediatric nephrology (Berlin, Germany) · 2023Pooled it
- Epidemiology and risk factors for avascular necrosis in childhood systemic lupus erythematosus in a Taiwanese population.Scientific reports · 2020Article
- Serum-soluble CXCL16 in juvenile systemic lupus erythematosus: a promising predictor of disease severity and lupus nephritis.Clinical rheumatology · 2018Article
- Missed opportunities for timely diagnosis of pediatric lupus in South Africa: a qualitative study.Pediatric rheumatology online journal · 2017Article
- Article
- Childhood versus adult-onset systemic lupus erythematosus: long-term outcome and predictors of mortality.Clinical rheumatology · 2017Article
- Clinicopathological findings and outcome of lupus nephritis in Tunisian children: a review of 43 patients.The Pan African medical journal · 2017Article
- Lupus nephritis in Egyptian children: a 16-year experience.Journal of nephrology · 2015Article
- Juvenile systemic lupus erythematosus onset patterns in Vietnamese children: a descriptive study of 45 children.Pediatric rheumatology online journal · 2012Article
- Clinical presentations and outcomes of Filipino juvenile systemic lupus erythematosus.Pediatric rheumatology online journal · 2011Article
- Clinical and laboratory variables of childhood systemic lupus erythematosus in western province of Saudi Arabia.Rheumatology international · 2011Article
- Understanding the epidemiology and progression of systemic lupus erythematosus.Seminars in arthritis and rheumatism · 2010Review
- A single-center experience of 13 Iranian children with lupus nephritis and pericarditis.International urology and nephrology · 2009Article
- Systemic lupus erythematosus in Egyptian children.Rheumatology international · 2009Article
- Childhood-onset systemic lupus erythematosus.Journal of the National Medical Association · 2007Article
- End-stage renal disease as the presenting manifestation of renal systemic lupus erythematosus.Pediatric nephrology (Berlin, Germany) · 2007Article
- Lupus nephropathy and cardiopulmonary and hepatic dysfunctions in a child.Pediatric nephrology (Berlin, Germany) · 2006Article
- Urinary Neutrophil Gelatinase-Associated Lipocalin and Urinary Soluble CXCL16 as Biomarkers of Activity in Pediatric Lupus Nephritis.Indian journal of nephrologyArticle
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Abstract
To highlight the characteristics of Egyptian children with systemic lupus erythematosus (SLE), the records of 52 SLE patients (48 girls and four boys aged 11.9+/-2.6 years) were retrospectively analyzed. The median duration of follow up was 22 months (range 1-94.5). The most common extrarenal manifestation was fever (76.6%), followed by joint involvement (65.4%). Hemolytic anemia was demonstrated in 51%, thrombocytopenia in 29.2%, and leucopenia in 27.5%. Antinuclear antibodies were positive in 92.7%, while positive anti-double-stranded DNA and hypocomplementemia were demonstrated in 95.6% and 67.4%, respectively. Lupus nephritis (LN) was evident in 80.8%. The renal manifestations of LN patients were proteinuria (83.3%), hematuria (71.5%), hypertension (35.7%), and elevated serum creatinine (16.7%). The histopathological findings of the initial renal biopsies were class I (4.9%), class II (22%), class III (36.3%), and class IV (36.3%). Among patients without LN, 85.7% gained remission and nonimmediately died. At last observation, 55.6% of LN patients had complete remission, 22.2% had active disease, and 22.2% died. Most patients who died had class IV LN. In conclusion, the characteristics of Egyptian SLE children are comparable with those in most Arab and Western series. However, LN may be more prevalent and severe, with unfavorable outcomes.
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