Trial reportJournal of applied physiology (Bethesda, Md. : 1985)2005
Laryngeal muscle responses to mechanical displacement of the thyroid cartilage in humans.
Trial report in Journal of applied physiology (Bethesda, Md. : 1985), 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 35 citations in OpenAlex.
- Beyond the jaw: vocal, oropharyngeal and cognitive-linguistic biomarkers for precision pain phenotyping in TMD.Journal of oral & facial pain and headache · 2026Review
- Auditory and somatosensory feedback mechanisms of laryngeal and articulatory speech motor control.Experimental brain research · 2022Article
- Functional anatomy of the vagus system - Emphasis on the somato-visceral interface.Autonomic neuroscience : basic & clinical · 2021Article
- Article
- Contributions of Auditory and Somatosensory Feedback to Vocal Motor Control.Journal of speech, language, and hearing research : JSLHR · 2020Article
- Laryngeal vibration as a non-invasive neuromodulation therapy for spasmodic dysphonia.Scientific reports · 2019Article
- Laryngeal Vibration Increases Spontaneous Swallowing Rates in Chronic Oropharyngeal Dysphagia: A Proof-of-Principle Pilot Study.Dysphagia · 2019Article
- Intermittent theta burst stimulation over right somatosensory larynx cortex enhances vocal pitch-regulation in nonsingers.Human brain mapping · 2019Article
- The Relationship Between Physiological Mechanisms and the Self-Perception of Vocal Effort.Journal of speech, language, and hearing research : JSLHR · 2019Article
- The relationship between acoustical and perceptual measures of vocal effort.The Journal of the Acoustical Society of America · 2018Article
- Voice-related modulation of mechanosensory detection thresholds in the human larynx.Experimental brain research · 2014Article
- Use of surface electromyography in phonation studies: an integrative review.International archives of otorhinolaryngology · 2013Review
- Covariation among vowel height effects on acoustic measures.The Journal of the Acoustical Society of America · 2011Article
- Laryngeal electromyographic responses to perturbations in voice pitch auditory feedback.The Journal of the Acoustical Society of America · 2011Article
- Design of a new somatosensory stimulus delivery device for measuring laryngeal mechanosensory detection thresholds in humans.IEEE transactions on bio-medical engineering · 2009Article
- Nonlinear source-filter coupling in phonation: vocal exercises.The Journal of the Acoustical Society of America · 2008Article
- Laryngeal reflex responses are not modulated during human voice and respiratory tasks.The Journal of physiology · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Speakers may use laryngeal sensory feedback to adjust vocal fold tension and length before initiating voice. The mechanism for accurately initiating voice at an intended pitch is unknown, given the absence of laryngeal muscle spindles in animals and conflicting findings regarding their existence in humans. Previous reports of rapid changes in voice fundamental frequency following thyroid cartilage displacement suggest that changes in vocal fold length modulate laryngeal muscle contraction in humans. We tested the hypothesis that voice changes resulting from mechanical perturbation are due to rapid responses in the intrinsic laryngeal muscles. Hooked wire electrodes were used to record from the thyroarytenoid, cricothyroid, and sternothyroid muscles along with surface electrodes on the skin overlying the thyroid cartilage in 10 normal adults. Servomotor displacements produced consistent changes in the subjects' vocal fundamental frequency at 70-80 ms, demonstrating changes in vocal fold length and tension. No simultaneous electromyographic responses occurred in the thyroarytenoid or cricothyroid muscles in any subjects. Instead, short-latency responses at 25-40 ms following stimulus onset occurred in the sternothyroid muscles, simultaneous with responses in the surface recordings. The sternothyroid responses may modulate long-latency changes in voice fundamental frequency (approximately 150 ms). The absence of intrinsic laryngeal muscle responses is consistent with a lack of spindles in these muscles. Our results suggest that other sensory receptors, such as mucosal mechanoreceptors, provide feedback for voice control.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.