ReviewThe Journal of clinical investigation2005
Linkage disequilibrium maps and association mapping.
Review in The Journal of clinical investigation, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Genetic Variation and Haplotype Structure ofLife (Basel, Switzerland) · 2026Article
- Genome-Environment Associations, an Innovative Tool for Studying Heritable Evolutionary Adaptation in Orphan Crops and Wild Relatives.Frontiers in genetics · 2022Review
- Genetic dissection of adventitious shoot regeneration in roses by employing genome-wide association studies.Plant cell reports · 2017Article
- High-Resolution Genetic Maps Identify Multiple Type 2 Diabetes Loci at Regulatory Hotspots in African Americans and Europeans.American journal of human genetics · 2017Article
- The Decay of Disease Association with Declining Linkage Disequilibrium: A Fine Mapping Theorem.Frontiers in genetics · 2016Article
- Genotype matrix mapping: searching for quantitative trait loci interactions in genetic variation in complex traits.DNA research : an international journal for rapid publication of reports on genes and genomes · 2007Article
- Magnetic resonance imaging as a tool for in vivo and ex vivo anatomical phenotyping in experimental genetic models.Human brain mapping · 2007Article
- Article
- Host susceptibility to persistent hepatitis B virus infection.World journal of gastroenterology · 2006Article
- Microarray technology in obstetrics and gynecology: a guide for clinicians.American journal of obstetrics and gynecology · 2006Review
- Mapping the new frontier: complex genetic disorders.The Journal of clinical investigation · 2005Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The causal chain between a gene and its effect on disease susceptibility cannot be understood until the effect has been localized in the DNA sequence. Recently, polymorphisms incorporated in the HapMap Project have made linkage disequilibrium (LD) the most powerful tool for localization. The genetics of LD, the maps and databases that it provides, and their use for association mapping, as well as alternative methods for gene localization, are briefly described.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.