ReviewThe Journal of clinical investigation2005
Mapping quantitative trait loci in humans: achievements and limitations.
Review in The Journal of clinical investigation, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Association analyses of repeated measures on triglyceride and high-density lipoprotein levels: insights from GAW20.BMC genetics · 2018Article
- The Generalized Relative Pairs IBD Distribution: Its Use in the Detection of Linkage.Frontiers in public health · 2016Article
- A two-step genetic study on quantitative precursors of coronary artery disease in a homogeneous Indian population: case-control association discovery and validation by transmission-disequilibrium test.Journal of biosciences · 2011Article
- Vaccinomics and a new paradigm for the development of preventive vaccines against viral infections.Omics : a journal of integrative biology · 2011Review
- Statistical Optimization of Pharmacogenomics Association Studies: Key Considerations from Study Design to Analysis.Current pharmacogenomics and personalized medicine · 2011Article
- Family-based mapping of quantitative trait loci in plant breeding populations with resistance to Fusarium head blight in wheat as an illustration.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2009Article
- Application of pharmacogenomics to vaccines.Pharmacogenomics · 2009Review
- Genome-wide association analyses of quantitative traits: the GAW16 experience.Genetic epidemiology · 2009Article
- Article
- Genotype matrix mapping: searching for quantitative trait loci interactions in genetic variation in complex traits.DNA research : an international journal for rapid publication of reports on genes and genomes · 2007Article
- Separation of base allele and sampling term effects gives new insights in variance component QTL analysis.BMC genetics · 2007Article
- Article
- Mapping the new frontier: complex genetic disorders.The Journal of clinical investigation · 2005Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent advances in statistical methods and genomic technologies have ushered in a new era in mapping clinically important quantitative traits. However, many refinements and novel statistical approaches are required to enable greater successes in this mapping. The possible impact of recent findings pertaining to the structure of the human genome on efforts to map quantitative traits is yet unclear.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.