ReviewClinical medicine & research2004
Categorizing asthma severity: an overview of national guidelines.
Review in Clinical medicine & research, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 52 citations in OpenAlex.
- Pooled it
- Effects of physical exercise training on nocturnal symptoms in asthma: Systematic review.PloS one · 2018Pooled it
- Association between dimensions of trauma-related psychopathology and asthma in trauma-exposed women.Frontiers in behavioral neuroscience · 2023Article
- Article
- MUC7 VNTR polymorphism and association with bronchial asthma in Egyptian children.Scientific reports · 2022Article
- Caregiver-perceived neighborhood safety and pediatric asthma severity: 2017-2018 National Survey of Children's Health.Pediatric pulmonology · 2022Article
- A review on the effect of COVID-19 in type 2 asthma and its management.International immunopharmacology · 2021Review
- Characteristics of Treated Asthmatics Experiencing Exacerbations in a US Database: A Retrospective Cohort Study.Journal of asthma and allergy · 2021Article
- Real-World Assessment of Asthma Control and Severity in Children, Adolescents, and Adults with Asthma: Relationships to Care Settings and Comorbidities.The journal of allergy and clinical immunology. In practice · 2020Article
- Equine asthma: Integrative biologic relevance of a recently proposed nomenclature.Journal of veterinary internal medicine · 2018Review
- Vitamin D deficiency and its impact on asthma severity in asthmatic children.Italian journal of pediatrics · 2016Article
- Health-Related Quality of Life of Children with Asthma: Self and Parental Perceptions.International journal of behavioral medicine · 2016Article
- Prevalence and severity of asthmatic symptoms in Grenadian school children: the Grenada National Asthma Survey.BMJ open · 2015Article
- History of guidelines for the diagnosis and management of asthma: from opinion to control.Drugs · 2009Review
- International differences in asthma guidelines for children.International archives of allergy and immunology · 2009Review
- Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute's Severe Asthma Research Program.The Journal of allergy and clinical immunology · 2007Article
- The evolving guideline.Clinical medicine & research · 2004Article
- The need for a meaningful and practical classification of asthma severity.Clinical medicine & research · 2004Article
- Similarities and differences between asthma health care professional and patient views regarding medication adherence.Canadian respiratory journalArticle
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Asthma is an inflammatory disease of the airways associated with intermittent episodes of bronchospasm. Corticosteroids are the most effective anti-inflammatory class of medication currently available for the treatment of asthma. However, as higher doses of inhaled corticosteroids are used the risks of systemic exposure and side effects will correspondingly increase. Justification of the benefits from higher doses of inhaled corticosteroids can only be made if patients with more severe asthma can be identified. Methods to categorize asthma severity have been introduced in various national asthma management guidelines. Unfortunately, there are substantial conceptual and practical differences among these recommended approaches to asthma severity categorization. Furthermore, these recommended approaches suffer from a focus on features of asthma control, such as symptoms, short-acting beta-agonist use, and lung function rather than actual measures of asthma severity that would encompass markers of airway inflammation. Without the endpoints necessary to assess airway inflammation, current recommendations for asthma severity categorization may lead to systematic under dosing of appropriate anti-inflammatory therapy with subsequent perpetuation of the asthma exacerbation cycle.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.