ArticleGenome research2005
Genome-wide prediction of imprinted murine genes.
Article in Genome research, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 126 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
126 citing papers in PubMed, 254 citations in OpenAlex.
- Non-Mendelian inheritance of DNA methylation patterns in mice.Nature genetics · 2026Article
- Epigenetics, human imprintome, and chronic diseases.Essays in biochemistry · 2025Review
- Candidate imprinting control regions in dog genome.BMC genomics · 2025Article
- PLP1-Targeting Antisense Oligonucleotides Improve FOXG1 Syndrome Mice.International journal of molecular sciences · 2024Article
- Livestock species as emerging models for genomic imprinting.Frontiers in cell and developmental biology · 2024Review
- Defining Candidate Imprinted loci inGenes · 2023Article
- Origin and Evolution of Marsupial-specific Imprinting Clusters Through Lineage-specific Gene Duplications and Acquisition of Promoter Differential Methylation.Molecular biology and evolution · 2023Article
- Genomic map of candidate human imprint control regions: the imprintome.Epigenetics · 2022Article
- A comparative methylome analysis reveals conservation and divergence of DNA methylation patterns and functions in vertebrates.BMC biology · 2022Article
- Detection of Genomic Imprinting for Carcass Traits in Cattle Using Imputed High-Density Genotype Data.Frontiers in genetics · 2022Article
- Discovering candidate imprinted genes and imprinting control regions in the human genome.BMC genomics · 2020Article
- Genome-wide allele-specific methylation is enriched at gene regulatory regions in a multi-generation pedigree from the Norfolk Island isolate.Epigenetics & chromatin · 2019Article
- Technical advances contribute to the study of genomic imprinting.PLoS genetics · 2019Review
- Characterization of bovine (Bos taurus) imprinted genes from genomic to amino acid attributes by data mining approaches.PloS one · 2019Article
- A genome-wide search for new imprinted genes in the human placenta identifies DSCAM as the first imprinted gene on chromosome 21.European journal of human genetics : EJHG · 2019Article
- Identification of DNA-Methylated CpG Islands Associated With Gene Silencing in the Adult Body Tissues of the Ogye Chicken Using RNA-Seq and Reduced Representation Bisulfite Sequencing.Frontiers in genetics · 2019Article
- Genome-wide survey of parent-of-origin effects on DNA methylation identifies candidate imprinted loci in humans.Human molecular genetics · 2018Article
- Machine learning for epigenetics and future medical applications.Epigenetics · 2017Review
- Genome-wide random regression analysis for parent-of-origin effects of body composition allometries in mouse.Scientific reports · 2017Article
- Conservation of Repeats at the Mammalian KCNQ1OT1-CDKN1C Region Suggests a Role in Genomic Imprinting.Evolutionary bioinformatics online · 2017Article
66 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
Imprinted genes are epigenetically modified genes whose expression is determined according to their parent of origin. They are involved in embryonic development, and imprinting dysregulation is linked to cancer, obesity, diabetes, and behavioral disorders such as autism and bipolar disease. Herein, we train a statistical model based on DNA sequence characteristics that not only identifies potentially imprinted genes, but also predicts the parental allele from which they are expressed. Of 23,788 annotated autosomal mouse genes, our model identifies 600 (2.5%) to be potentially imprinted, 64% of which are predicted to exhibit maternal expression. These predictions allowed for the identification of putative candidate genes for complex conditions where parent-of-origin effects are involved, including Alzheimer disease, autism, bipolar disorder, diabetes, male sexual orientation, obesity, and schizophrenia. We observe that the number, type, and relative orientation of repeated elements flanking a gene are particularly important in predicting whether a gene is imprinted.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.