Evidence map›Paper›PMID 15930025›Full record

SynthesisBMJ (Clinical research ed.)2005

Ultrasonography in screening for developmental dysplasia of the hip in newborns: systematic review.

Nerys F Woolacott, Milo A Puhan, Johann Steurer, Jos Kleijnen

Registry-linked trialOpen access · bronzeAbstract readSystematic Review
In one paragraph

Synthesis in BMJ (Clinical research ed.), 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03275805 (How Should Stable Graf Type IIc Hips be Treated With Pavlik Harness?), which is not on this map. Cited by 45 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 3 pooled it
7.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03275805 naterminatednot on this mapstarted 2021, after this paper: background citation

How Should Stable Graf Type IIc Hips be Treated With Pavlik Harness?

TypeinterventionalSponsorUniversity of Colorado, DenverRan2021 to 2025Enrolled20ConditionsDevelopmental Dysplasia of HipArmsDuration of Pavlik Harness treatment, 12 week standard of care
3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 3 syntheses or guidelines pooled it, 143 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Nerys F WoolacottCentre for Reviews and Dissemination, University of York, York YO10 5DD. nw11@york.ac.uk <nw11@york.ac.uk>
Milo A Puhan
Johann Steurer
Jos Kleijnen
University of York · GBUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the accuracy and effectiveness of the screening of all newborn infants for developmental dysplasia of the hip (DDH) using ultrasound imaging, as is standard practice in some European countries but not in the United Kingdom, the United States, or Scandinavia.

designSystematic review. DATA SOURCES: Twenty three medical, economic, and grey literature databases (to March 2004), with no limitations of design or language; some references were provided by experts. SELECTION OF STUDIES: Only diagnostic accuracy studies and comparative studies conducted in an unselected newborn population were eligible for the review. Two reviewers independently selected the studies and performed the quality assessment.

resultsThe review identified one diagnostic accuracy study, and this was of limited quality. In this study the reference standard was treatment up to age of 8 months or an abnormal ultrasound finding at age 8 months. Ultrasound screening had a sensitivity of 88.5% (95% confidence interval 84.1% to 92.1%), specificity of 96.7% (96.4% to 97.4%), a positive predictive value of 61.6% and a negative predictive value of 99.4%. Ten studies evaluated the impact of ultrasound in screening, but these too had various methodological weaknesses, limiting the reliability of their findings. Compared with clinical screening, general ultrasound screening in newborns may increase overall treatment rates, but ultrasound screening seems to be associated with shorter and less intrusive treatment.

conclusionsClear evidence is lacking either for or against general ultrasound screening of newborn infants for DDH. Studies that investigate the natural course of the disorder, the optimal treatment for DDH, and the best strategy for ultrasound screening are needed.

Indexed as

Clinical Trials as TopicEarly DiagnosisHip Dislocation, CongenitalHumansInfantInfant, NewbornNeonatal ScreeningRandomized Controlled Trials as TopicSensitivity and SpecificityUltrasonography

Identifiers

PMID15930025
PMCPMC558371
OpenAlexW2105782937

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.