Evidence map›Paper›PMID 15928914›Full record

ReviewSpringer seminars in immunopathology2005

Intestinal mucosal responses to microbial infection.

Lars Eckmann, Martin F Kagnoff

Abstract readReview
PubMed Publisher
In one paragraph

Review in Springer seminars in immunopathology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Lars EckmannDepartment of Medicine, University of California at San Diego, La Jolla, CA 92093, USA.
Martin F Kagnoff
University of California, San Diego · US

Funding

TL MOLECULES AND GAMMA-DELTA T CELLSP01DK035108 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI KAGNOFF, MARTIN FREDERICK · 1986 to 2013
$19.2M
INTESTINAL EPITHELIAL RESPONSES TO FOOD BORNE PATHOGENSR01DK058960 · NIDDK · UNIVERSITY OF CALIFORNIA SAN DIEGO · PI KAGNOFF, MARTIN FREDERICK · 2000 to 2004
$1.4M
HOST DEFENSES AGAINST PATHOGENIC E. coliR01AI056075 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ECKMANN, LARS · 2003 to 2007
$1.3M
MOUSE MODELS OF INTESTINAL INFECTION AND INFLAMMATIONK26RR017030 · NCRR · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ECKMANN, LARS · 2004 to 2008
$457k
NCRR NIH HHS RR17030NIAID NIH HHS AI56075NIDDK NIH HHS DK35108NIDDK NIH HHS DK58960
6 · The paper itself

Abstract

Infections of the human intestinal tract with foodborne and waterborne pathogens are among the leading causes of morbidity and death in the world. Upon ingestion, such pathogens commonly pass through the stomach in sufficient numbers to establish infection in the small intestine or colon. The subsequent interactions with the host depend critically on the particular pathogen, ranging from mere presence in the intestinal lumen and minimal interaction with the epithelium to highly mucosal invasive with rapid systemic spread. This article addresses the morphological and molecular changes that occur in the intestinal mucosa after infection with a selected yet representative spectrum of enteric pathogens, ranging from luminally restricted but epithelial adherent, epithelial invasive, to mucosally invasive, with a focus on intestinal epithelial responses.

Indexed as

AnimalsBacterial InfectionsCathelicidinsCytokinesDefensinsHumansInflammation MediatorsIntestinal DiseasesIntestinal Diseases, ParasiticIntestinal MucosaIntestinesMacrophagesNeutrophilsCathelicidinsCytokinesDefensinsInflammation Mediators

Identifiers

PMID15928914
OpenAlexW1967757371

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.