Evidence map›Paper›PMID 15927543›Full record

ReviewRespiratory physiology & neurobiology2005

Central nervous system control of the laryngeal muscles in humans.

Christy L Ludlow

Open access · greenAbstract readReview
In one paragraph

Review in Respiratory physiology & neurobiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 174 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Voice Meets Swallowing: A Scoping Review of Therapeutic Connections.American journal of speech-language pathology · 2025
    Article
  12. Review
  13. The speech neuroprosthesis.Nature reviews. Neuroscience · 2024
    Review
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Review

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Christy L LudlowLaryngeal and Speech Section, Medical Neurology Branch, National Institute of Neurological Disorders and Stroke/NIH, Building 10, Room 5D 38, 10 Center Drive MSC 1416, Bethesda, MD 20892, USA. ludlowc@ninds.nih.gov
National Institute of Neurological Disorders and Stroke · US

Funding

The Bases Of Normal And Disordered Laryngeal And Speech SystemsZIANS002980 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI LUDLOW, CHRISTY LESLIE · 2009 to 2009
$4.3M
THE BASES OF NORMAL AND DISORDERED LARYNGEAL AND SPEECH SYSTEMSZ01NS002980 · NINDS · NEUROLOGICAL DISORDERS AND STROKE · PI LUDLOW, CHRISTY LESLIE · 1999 to 2008
$3.5M
6 · The paper itself

Abstract

Laryngeal muscle control may vary for different functions such as: voice for speech communication, emotional expression during laughter and cry, breathing, swallowing, and cough. This review discusses the control of the human laryngeal muscles for some of these different functions. Sensori-motor aspects of laryngeal control have been studied by eliciting various laryngeal reflexes. The role of audition in learning and monitoring ongoing voice production for speech is well known; while the role of somatosensory feedback is less well understood. Reflexive control systems involving central pattern generators may contribute to swallowing, breathing and cough with greater cortical control during volitional tasks such as voice production for speech. Volitional control is much less well understood for each of these functions and likely involves the integration of cortical and subcortical circuits. The new frontier is the study of the central control of the laryngeal musculature for voice, swallowing and breathing and how volitional and reflexive control systems may interact in humans.

Indexed as

BrainCoughHumansLaryngeal MusclesLaryngismusRespiratory MechanicsSpeechVoice

Identifiers

PMID15927543
PMCPMC1351146
OpenAlexW2028072567

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.