ArticleEuropean journal of pediatrics2005
Risk factors for allergic bronchopulmonary aspergillosis and sensitisation to Aspergillus fumigatus in patients with cystic fibrosis.
Article in European journal of pediatrics, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 52 citations in OpenAlex.
- Review
- Longitudinal Study on Clinical Predictors for Allergic Bronchopulmonary Aspergillosis in Children and Young People with Cystic Fibrosis Highlights the Impact of Infection withJournal of fungi (Basel, Switzerland) · 2025Article
- Clinical Impact ofMicroorganisms · 2022Article
- Allergic bronchopulmonary Aspergillosis in children.Turkish journal of medical sciences · 2021Article
- Increased Incidence and Associated Risk Factors of Aspergillosis in Patients with Bronchiectasis.Journal of personalized medicine · 2021Article
- Article
- Risk factors for persistent Aspergillus respiratory isolation in cystic fibrosis.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2018Article
- Omalizumab in allergic bronchopulmonary aspergillosis in patients with cystic fibrosis.Journal of asthma and allergy · 2018Article
- Use of Selective Fungal Culture Media Increases Rates of Detection of Fungi in the Respiratory Tract of Cystic Fibrosis Patients.Journal of clinical microbiology · 2017Article
- Concomitant presence of Aspergillus fumigatus and Stenotrophomonas maltophilia in the respiratory tract: a new risk for patients with liver disease?Journal of medical microbiology · 2016Article
- Characteristics of Aspergillus fumigatus in Association with Stenotrophomonas maltophilia in an In Vitro Model of Mixed Biofilm.PloS one · 2016Article
- Stenotrophomonas, Mycobacterium, and Streptomyces in home dust and air: associations with moldiness and other home/family characteristics.Indoor air · 2013Article
- Pneumomediastinum as a presenting feature of allergic bronchopulmonary aspergillosis in a child with cystic fibrosis.Journal of the Royal Society of Medicine · 2012Article
- Rapid identification of allergenic and pathogenic molds in environmental air by an oligonucleotide array.BMC infectious diseases · 2011Article
- The changing microbial epidemiology in cystic fibrosis.Clinical microbiology reviews · 2010Review
- Prevalence and risk factors for recovery of filamentous fungi in individuals with cystic fibrosis.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2010Article
- Th2 allergic immune response to inhaled fungal antigens is modulated by TLR-4-independent bacterial products.European journal of immunology · 2009Article
- Childhood allergic bronchopulmonary aspergillosis.Lung India : official organ of Indian Chest SocietyReview
Corrections and comments
- Erratum issued
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelledAn increasing incidence of allergic bronchopulmonary aspergillosis (ABPA) as a complication in patients with cystic fibrosis (CF) is reported. The objective of this retrospective case-control study was to assess potential risk factors for ABPA and for Aspergillus fumigatus sensitisation (AFS). In a group of 160 CF patients, 11 (7%) fulfilled the diagnostic criteria for ABPA and 20 (13%) had evidence of AFS. They were compared to 62 control CF patients (25 for ABPA and 37 for AFS group) without evidence of ABPA or AFS using extended matching for sex, age and weight. AFS patients had received significantly higher cumulative doses of inhaled corticosteroids than their respective controls (OR 8.0; 95% CI 1.74-63). Bronchial colonisation with Stenotrophomonas maltophilia was strongly and independently associated with ABPA (OR 20; 95% CI 2.8- infinity). A longer duration of Pseudomonas aeruginosa colonisation was independently associated with AFS (OR per year 1.50; 95% CI 1.12- infinity).
conclusionCystic fibrosis patients with allergic bronchopulmonary aspergillosis have a more frequent isolation of S. maltophilia in their sputum than their controls. Longer duration of colonisation with P. aeruginosa is a risk factor for Aspergillus fumigatus sensitisation. Higher cumulative doses of inhaled corticosteroids are associated with Aspergillus fumigatus sensitisation and their role as a risk factor needs to be clarified.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.