ArticlePlant physiology2005
The Arabidopsis plastidic methionine sulfoxide reductase B proteins. Sequence and activity characteristics, comparison of the expression with plastidic methionine sulfoxide reductase A, and induction by photooxidative stress.
Article in Plant physiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.
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Who cites it
62 citing papers in PubMed, 158 citations in OpenAlex.
- Protein turnover in plants-cost of synthesis, repair, and crop engineering opportunities.Plant physiology · 2026Review
- Interaction with CYP20-3 limits OPDA flux into jasmonate biosynthesis in wounded leaves of arabidopsis grown at eCOFrontiers in plant science · 2026Article
- Peptides and Reactive Oxygen Species Regulate Root Development.International journal of molecular sciences · 2025Review
- Integrating transcriptome and metabolome analyses to characterize flower development in Salix variegata franch., a typical dioecious plant.Scientific reports · 2025Article
- The association of protein-bound methionine sulfoxide with proteomic basis for aging in beech seeds.BMC plant biology · 2024Article
- Genome-Wide Identification and Characterization of the Msr Gene Family in Alfalfa under Abiotic Stress.International journal of molecular sciences · 2023Article
- Elucidating the molecular responses to waterlogging stress in onion (Frontiers in plant science · 2023Article
- A Novel Small RNA, DsrO, in Deinococcus radiodurans Promotes Methionine Sulfoxide Reductase (Applied and environmental microbiology · 2022Article
- MTO1-RESPONDING DOWN 1 (MRD1) is a transcriptional target of OZF1 for promoting salicylic acid-mediated defense in Arabidopsis.Plant cell reports · 2022Article
- Type-A response regulators negatively mediate heat stress response by altering redox homeostasis in Arabidopsis.Frontiers in plant science · 2022Article
- Localization and Dynamics of the Methionine Sulfoxide Reductases MsrB1 and MsrB2 in Beech Seeds.International journal of molecular sciences · 2021Article
- Integration of MsrB1 and MsrB2 in the Redox Network during the Development of Orthodox and RecalcitrantAntioxidants (Basel, Switzerland) · 2020Article
- Involvement of the MetO/Msr System in TwoInternational journal of molecular sciences · 2020Article
- Peptide-Bound Methionine Sulfoxide (MetO) Levels and MsrB2 Abundance Are Differentially Regulated during the Desiccation Phase in ContrastedAntioxidants (Basel, Switzerland) · 2020Article
- Methionine sulfoxide reductase B fromThe Journal of biological chemistry · 2020Article
- Pure Organic Active Compounds Against Abiotic Stress: A Biostimulant Overview.Frontiers in plant science · 2020Review
- Regulation of Gene Expression of Methionine Sulfoxide Reductases and Their New Putative Roles in Plants.International journal of molecular sciences · 2019Article
- Physiological Roles of Plant Methionine Sulfoxide Reductases in Redox Homeostasis and Signaling.Antioxidants (Basel, Switzerland) · 2018Review
- Monitoring of Methionine Sulfoxide Content and Methionine Sulfoxide Reductase Activity.Methods in molecular biology (Clifton, N.J.) · 2018Article
- Integrative Transcriptomic Analysis Uncovers Novel Gene Modules That Underlie the Sulfate Response inFrontiers in plant science · 2018Article
2 more citing papers are in PubMed but not listed here.
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Two types of methionine (Met) sulfoxide reductases (Msr) catalyze the reduction of Met sulfoxide (MetSO) back to Met. MsrA, well characterized in plants, exhibits an activity restricted to the Met-S-SO-enantiomer. Recently, a new type of Msr enzyme, called MsrB, has been identified in various organisms and shown to catalytically reduce the R-enantiomer of MetSO. In plants, very little information is available about MsrB and we focused our attention on Arabidopsis (Arabidopsis thaliana) MsrB proteins. Searching Arabidopsis genome databases, we have identified nine open reading frames encoding proteins closely related to MsrB proteins from bacteria and animal cells. We then analyzed the activity and abundance of the two chloroplastic MsrB proteins, MsrB1 and MsrB2. Both enzymes exhibit an absolute R-stereospecificity for MetSO and a higher catalytic efficiency when using protein-bound MetSO as a substrate than when using free MetSO. Interestingly, we observed that MsrB2 is reduced by thioredoxin, whereas MsrB1 is not. This feature of MsrB1 could result from the lack of the catalytical cysteine (Cys) corresponding to Cys-63 in Escherichia coli MsrB that is involved in the regeneration of Cys-117 through the formation of an intramolecular disulfide bridge followed by thioredoxin reduction. We investigated the abundance of plastidial MsrA and B in response to abiotic (water stress, photooxidative treatment) and biotic (rust fungus) stresses and we observed that MsrA and B protein levels increase in response to the photooxidative treatment. The possible role of plastidic MsrB in the tolerance to oxidative damage is discussed.
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