Evidence map›Paper›PMID 15923280›Full record

ArticleHeart (British Cardiac Society)2006

Sudden adult death syndrome and other non-ischaemic causes of sudden cardiac death.

A Fabre, M N Sheppard

2 registry-linked trialsOpen access · bronzeAbstract read
In one paragraph

Article in Heart (British Cardiac Society), 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 119 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
119citing papers in PubMed, 4 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05158751 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Myocarditis Causing Premature Ventricular Contractions:Insights From the MAVERIC Registry

TypeobservationalSponsorKansas City Heart Rhythm Research FoundationRan2026 to 2026Enrolled100ConditionsMyocarditis, Premature Ventricular Contractions, Ventricular Tachycardia (VT)
NCT06060548 recruitingnot on this mapstarted 2022, after this paper: background citation

Role of a Novel Implantable Loop Recorder in the Management of Premature Ventricular Contractions

TypeobservationalSponsorKansas City Heart Rhythm Research FoundationRan2022 to 2025Enrolled50ConditionsPVC - Premature Ventricular Contraction, MyocarditisArmsMonitoring of patients presenting with PVCs
3 · Its place in the literature

Who cites it

119 citing papers in PubMed, 4 syntheses or guidelines pooled it, 334 citations in OpenAlex.

  1. Brazilian Society of Cardiology Guideline on Myocarditis - 2022.Arquivos brasileiros de cardiologia · 2022
    Guideline
  2. Pooled it
  3. Guideline
  4. Guidelines for autopsy investigation of sudden cardiac death.Virchows Archiv : an international journal of pathology · 2008
    Guideline
  5. Trial
  6. Article
  7. Review
  8. Health profiles and lifestyles of those with cardiomyopathyThe British journal of cardiology · 2026
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Infectious factors in myocarditis: a comprehensive review of common and rare pathogens.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2024
    Review
  19. Article
  20. Article

59 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

A FabreDepartment of Pathology, Royal Brompton and Harefield NHS Trust, London, UK.
M N Sheppard
Royal Brompton & Harefield NHS Foundation Trust · GBRoyal Brompton Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate non-atherosclerotic cardiac deaths in the UK population aged over 15 years including elderly patients and to highlight the concept of the structurally normal heart in sudden death.

methodsPathological data were collected prospectively for sudden adult deaths referred by UK coroners.

results453 cases of sudden death from 1994 to 2003 (278 men (61.4%) and 175 women (38.6%), age range 15-81 years) were reviewed. Males predominated in both age groups (< or = 35 years, > 35 years). More than half of the hearts (n = 269, 59.3%) were structurally normal. In the other 40.7%, cardiac abnormalities were noted, which included: (1) cardiomyopathies (23%) such as idiopathic fibrosis, left ventricular hypertrophy, hypertrophic cardiomyopathy, dilated cardiomyopathy, and arrhythmogenic right ventricular dysplasia; (2) inflammatory disorders (8.6%) including lymphocytic myocarditis and cardiac sarcoidosis; (3) non-atheromatous abnormalities of coronary arteries (4.6%); (4) valve diseases; and (5) miscellaneous and rare causes.

conclusionThe concept of the structurally normal heart in sudden death and the need for histological examination to detect underlying disease is highlighted. Relatives need to be referred for cardiological and genetic screening in cases of normal hearts found at necropsy.

Indexed as

AdolescentAdultAgedAged, 80 and overAge DistributionCardiomyopathiesCoronary Vessel AnomaliesDeath, Sudden, CardiacFemaleHeart Conduction SystemHeart Defects, CongenitalHeart Valve DiseasesHumansLondonMaleMiddle Aged

Identifiers

PMID15923280
PMCPMC1860827
OpenAlexW2115350314

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.