ArticleThorax2005
Association between short term exposure to fine particulate matter and heart rate variability in older subjects with and without heart disease.
Article in Thorax, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 68 citations in OpenAlex.
- An epidemiological appraisal of the association between heart rate variability and particulate air pollution: a meta-analysis.Heart (British Cardiac Society) · 2012Pooled it
- Cardiovascular effects of sub-daily levels of ambient fine particles: a systematic review.Environmental health : a global access science source · 2010Pooled it
- Air pollution exposure and cardiometabolic risk.The lancet. Diabetes & endocrinology · 2024Review
- The pulmonary and autonomic effects of high-intensity and low-intensity exercise in diesel exhaust.Environmental health : a global access science source · 2018Article
- The Acute Effects of Age and Particulate Matter Exposure on Heart Rate and Heart Rate Variability in Mice.Cardiovascular toxicology · 2018Article
- Evaluation of vulnerable PMEnvironmental science and pollution research international · 2018Article
- Cytotoxicity of Air Pollutant 9,10-Phenanthrenequinone: Role of Reactive Oxygen Species and Redox Signaling.BioMed research international · 2018Review
- Association of air pollution sources and aldehydes with biomarkers of blood coagulation, pulmonary inflammation, and systemic oxidative stress.Journal of exposure science & environmental epidemiology · 2017Article
- Cardio-Respiratory Effects of Air Pollution in a Panel Study of Outdoor Physical Activity and Health in Rural Older Adults.Journal of occupational and environmental medicine · 2017Article
- Potential Occupational Exposures and Health Risks Associated with Biomass-Based Power Generation.International journal of environmental research and public health · 2015Review
- Impact of Fine Particulate Matter (PM2.5) Exposure During Wildfires on Cardiovascular Health Outcomes.Journal of the American Heart Association · 2015Article
- Children and elders exposure assessment to particle-bound polycyclic aromatic hydrocarbons (PAHs) in the city of Rome, Italy.Environmental science and pollution research international · 2014Article
- Cardiorespiratory biomarker responses in healthy young adults to drastic air quality changes surrounding the 2008 Beijing Olympics.Research report (Health Effects Institute) · 2013Article
- Effects of fine particulate on heart rate variability in Beijing: a panel study of healthy elderly subjects.International archives of occupational and environmental health · 2012Article
- Acute effects of fine particulate air pollution on cardiac arrhythmia: the APACR study.Environmental health perspectives · 2011Article
- Triggering of transmural infarctions, but not nontransmural infarctions, by ambient fine particles.Environmental health perspectives · 2010Article
- Particulate matter (PM) research centers (1999-2005) and the role of interdisciplinary center-based research.Environmental health perspectives · 2009Article
- Effects of diesel exhaust inhalation on heart rate variability in human volunteers.Environmental research · 2008Article
- Air pollution and mortality: are we closer to understanding the how?American journal of respiratory and critical care medicine · 2007Article
- Coarse particulate matter (PM2.5-10) affects heart rate variability, blood lipids, and circulating eosinophils in adults with asthma.Environmental health perspectives · 2007Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundShort term increases in exposure to particulate matter (PM) air pollution are associated with increased cardiovascular morbidity and mortality. The mechanism behind this effect is unclear, although changes in autonomic control have been observed. It was hypothesised that increases in fine PM measured at the subjects' home in the preceding hour would be associated with decreased high frequency heart rate variability (HF-HRV) in individuals with pre-existing cardiac disease.
methodsTwo hundred and eighty five daily 20 minute measures of HRV (including a paced breathing protocol) were made in the homes of 34 elderly individuals with (n = 21) and without (n = 13) cardiovascular disease (CVD) over a 10 day period in Seattle between February 2000 and March 2002. Fine PM was continuously measured by nephelometry at the individuals' homes.
resultsThe median age of the study population was 77 years (range 57-87) and 44% were male. Models that adjusted for health status, relative humidity, temperature, mean heart rate, and medication use did not find a significant association between a 10 microg/m3 increase in 1 hour mean outdoor PM2.5 before the HRV measurement and a change in HF-HRV power in individuals with CVD (3% increase in median HF-HRV (95% CI -19 to 32)) or without CVD (5% decrease in median HF-HRV (95% CI -34 to 36)). Similarly, no association was evident using 4 hour and 24 hour mean outdoor PM2.5 exposures before the HRV measurement.
conclusionNo association was found between increased residence levels of fine PM and frequency domain measures of HRV in elderly individuals.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.