ArticleBMC genomics2005
Insights into a dinoflagellate genome through expressed sequence tag analysis.
Article in BMC genomics, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
55 citing papers in PubMed, 149 citations in OpenAlex.
- The enigmatic nucleus of the marine dinoflagellatemSphere · 2023Article
- Genomic copy number variability at the genus, species and population levels impacts in situ ecological analyses of dinoflagellates and harmful algal blooms.ISME communications · 2023Article
- SAG-RAD: A Method for Single-Cell Population Genomics of Unicellular Eukaryotes.Molecular biology and evolution · 2023Article
- The Evolution of the Cytochrome c6 Family of Photosynthetic Electron Transfer Proteins.Genome biology and evolution · 2021Article
- New Perspectives Related to the Bioluminescent System in Dinoflagellates:International journal of molecular sciences · 2020Review
- Omics Analysis for Dinoflagellates Biology Research.Microorganisms · 2019Review
- The Biochemistry and Evolution of the Dinoflagellate Nucleus.Microorganisms · 2019Review
- The Genetic Basis of Toxin Biosynthesis in Dinoflagellates.Microorganisms · 2019Review
- Expression of a symbiosis-specific gene inRoyal Society open science · 2017Article
- Review
- Paralytic shellfish toxin content is related to genomic sxtA4 copy number in Alexandrium minutum strains.Frontiers in microbiology · 2015Article
- Genomic insights into processes driving the infection of Alexandrium tamarense by the Parasitoid Amoebophrya sp.Eukaryotic cell · 2014Article
- Agrigenomics for microalgal biofuel production: an overview of various bioinformatics resources and recent studies to link OMICS to bioenergy and bioeconomy.Omics : a journal of integrative biology · 2013Review
- Understanding Bioluminescence in Dinoflagellates-How Far Have We Come?Microorganisms · 2013Review
- Evolution and distribution of saxitoxin biosynthesis in dinoflagellates.Marine drugs · 2013Review
- The case of horizontal gene transfer from bacteria to the peculiar dinoflagellate plastid genome.Mobile genetic elements · 2013Article
- "Eco-omics": a review of the application of genomics, transcriptomics, and proteomics for the study of the ecology of harmful algae.Microbial ecology · 2013Review
- Horizontal gene transfer is a significant driver of gene innovation in dinoflagellates.Genome biology and evolution · 2013Article
- Computational Identification of MicroRNAs from the Expressed Sequence Tags of Toxic Dinoflagellate Alexandrium Tamarense.Evolutionary bioinformatics online · 2013Article
- Evolution of saxitoxin synthesis in cyanobacteria and dinoflagellates.Molecular biology and evolution · 2013Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
backgroundDinoflagellates are important marine primary producers and grazers and cause toxic "red tides". These taxa are characterized by many unique features such as immense genomes, the absence of nucleosomes, and photosynthetic organelles (plastids) that have been gained and lost multiple times. We generated EST sequences from non-normalized and normalized cDNA libraries from a culture of the toxic species Alexandrium tamarense to elucidate dinoflagellate evolution. Previous analyses of these data have clarified plastid origin and here we study the gene content, annotate the ESTs, and analyze the genes that are putatively involved in DNA packaging.
resultsApproximately 20% of the 6,723 unique (11,171 total 3'-reads) ESTs data could be annotated using Blast searches against GenBank. Several putative dinoflagellate-specific mRNAs were identified, including one novel plastid protein. Dinoflagellate genes, similar to other eukaryotes, have a high GC-content that is reflected in the amino acid codon usage. Highly represented transcripts include histone-like (HLP) and luciferin binding proteins and several genes occur in families that encode nearly identical proteins. We also identified rare transcripts encoding a predicted protein highly similar to histone H2A.X. We speculate this histone may be retained for its role in DNA double-strand break repair.
conclusionThis is the most extensive collection to date of ESTs from a toxic dinoflagellate. These data will be instrumental to future research to understand the unique and complex cell biology of these organisms and for potentially identifying the genes involved in toxin production.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.