SynthesisBiological research for nursing2005
Allostatic load: a mechanism of socioeconomic health disparities?
Synthesis in Biological research for nursing, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
92 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Adrenocortical and autonomic cross-system regulation in youth: A meta-analysis.Psychoneuroendocrinology · 2024Pooled it
- Towards a consensus definition of allostatic load: a multi-cohort, multi-system, multi-biomarker individual participant data (IPD) meta-analysis.Psychoneuroendocrinology · 2023Pooled it
- Allostatic Load Measurement: A Systematic Review of Reviews, Database Inventory, and Considerations for Neighborhood Research.International journal of environmental research and public health · 2022Pooled it
- Pooled it
- Behavioral adjustment in a community sample of boys: links with basal and stress-induced salivary cortisol concentrations.Psychoneuroendocrinology · 2010Trial
- Contribution of short-term changes in a composite health score on pathways linking social disadvantage and health: evidence from the UK biobank prospective cohort study.EClinicalMedicine · 2026Article
- Allostatic Load Predicts Symptom Burden Among Breast Cancer Survivors.Research square · 2026Article
- How Scientific Is Nursing? Answers From A New Characterization of Science.Nursing philosophy : an international journal for healthcare professionals · 2026Article
- The past and future of integrated biopsychosocial whole-health perspectives in psychiatric rehabilitation.Psychiatric rehabilitation journal · 2026Review
- Dysglycemia-Based Chronic Disease and Lifestyle Medicine: Mechanistic Interpretation Using the Allostatic Load Model.American journal of lifestyle medicine · 2026Review
- CVD Environmental Health Disparities Tool: systematic evidence mapping of psychosocial stressors, environmental exposures, and cardiovascular diseases to inform disparities research and action.Environmental health : a global access science source · 2026Review
- Assessing Measurement Invariance in Allostatic Load between Black and White Adolescents.Journal of racial and ethnic health disparities · 2026Article
- Allostatic Load Mediates Associations Between Race and Ethnicity and Hypertensive Disorders of Pregnancy.Obstetrics and gynecology · 2026Article
- Review
- The impact of maternal chronic stress on spontaneous preterm birth: evidence from a Chinese cohort study.BMC pregnancy and childbirth · 2025Article
- Food insecurity and cognitive domains among older United States adults: Findings from the health and retirement study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Association of parity with the timing and type of menopause: a longitudinal cohort study.American journal of epidemiology · 2025Article
- Understanding disparities in firearm mortality: The role of person- and place-based factors.Injury · 2025Article
- Racial Disparities in COVID-19 Severity Are Partially Mediated by Chronic Stress-Evidence from a Large Integrated Healthcare System.Journal of racial and ethnic health disparities · 2025Observational
- Protocol of the HARMONY study: A culturally relevant, randomized-controlled, stress management intervention to reduce cardiometabolic risk in African American women.Contemporary clinical trials · 2024Article
32 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Although research on health disparities has been prioritized by the National Institutes of Health, the Institute of Medicine, and Healthy People 2010, little has been published that examines the biology underlying health disparities. Allostatic load is a multisystem construct theorized to quantify stress-induced biological risk. Differences in allostatic load may reflect differences in stress exposure and thus provide a mechanistic link to understanding health disparities. The purpose of this systematic review is to examine the construct of allostatic load and the published studies that employ it in an effort to understand whether the construct can be useful in quantifying health disparities. The published literature demonstrates that allostatic load is elevated in those of low socioeconomic status (SES) as compared to those of high SES. The reviewed articles vary in the justification for inclusion of variables. Recommendations for future research are made in the contexts of measurement, methodology, and racial composition of participants.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.