Evidence map›Paper›PMID 15919945›Full record

ArticleJournal of virology2005

Epstein-Barr virus BZLF1 protein binds to mitotic chromosomes.

Amy L Adamson

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Mitotic bookmarking by transcription factors.Epigenetics & chromatin · 2013
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Amy L AdamsonDepartment of Biology, University of North Carolina at Greensboro, Greensboro, NC 27402, USA. aladamso@uncg.edu
University of North Carolina at Greensboro · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epstein-Barr virus (EBV) is a human herpesvirus that causes infectious mononucleosis and is associated with several types of cancers, including nasopharyngeal carcinoma and Burkitt's lymphoma. An EBV protein that plays an integral role during lytic replication is the immediate-early protein BZLF1. Our laboratory has found that BZLF1 (Z) localizes to host chromosomes during mitosis. Two Z-interacting proteins are also found localized to mitotic chromosomes in the presence of Z. The association between Z and mitotic chromosomes may lead to the sequestering of Z-interacting proteins within the cell and potentially cause an alteration of chromosome compaction or chromatin structure.

Indexed as

MitosisAnimalsChromosomes, HumanChromosomes, MammalianCREB-Binding ProteinDNA-Binding ProteinsHeLa CellsHumansMiceNIH 3T3 CellsNuclear ProteinsPAX5 Transcription FactorTrans-ActivatorsTranscription FactorsTransfectionViral ProteinsBZLF1 protein, Herpesvirus 4, HumanCREB-Binding ProteinCREBBP protein, humanCrebbp protein, mouseDNA-Binding ProteinsNuclear ProteinsPAX5 protein, humanPax5 protein, mousePAX5 Transcription FactorTrans-ActivatorsTranscription FactorsViral Proteins

Identifiers

PMID15919945
PMCPMC1143656
OpenAlexW2133481060

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.