ArticleFunctional & integrative genomics2005
Genetic and in silico comparative mapping of the polyphenol oxidase gene in bread wheat (Triticum aestivum L.).
Article in Functional & integrative genomics, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 76 citations in OpenAlex.
- Rethinking polyphenol oxidases in wheat: beyond the "low-PPO is always better" paradigm.Frontiers in genetics · 2026Review
- Development and validation of a new co-dominant DNA marker for selecting the null allele of polyphenol oxidase geneBreeding science · 2025Article
- Identification and validation of genomic regions for pod shatter resistance in Brassica rapa using QTL-seq and traditional QTL mapping.BMC plant biology · 2025Article
- An Overview of Factors Affecting the Functional Quality of Common Wheat (International journal of molecular sciences · 2023Review
- Functional analysis of polyphenol oxidase 1 gene in common wheat.Frontiers in plant science · 2023Article
- Novel quantitative trait loci from an interspecificFrontiers in plant science · 2023Article
- Genome-Wide Association Analyses Track Genomic Regions for Resistance toFrontiers in plant science · 2022Article
- Molecular Diversity Analysis and Genetic Mapping of Pod Shatter Resistance Loci inFrontiers in plant science · 2017Article
- Genome-wide linkage mapping of flour color-related traits and polyphenol oxidase activity in common wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2016Article
- Genetic characterization and expression analysis of wheat (Triticum aestivum) line 07OR1074 exhibiting very low polyphenol oxidase (PPO) activity.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2015Article
- Genetic and physical mapping of flowering time loci in canola (Brassica napus L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2013Article
- Inheritance of grain polyphenol oxidase (PPO) activity in multiple wheat (Triticum aestivum L.) genetic backgrounds.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2012Article
- Molecular mapping of qualitative and quantitative loci for resistance to Leptosphaeria maculans causing blackleg disease in canola (Brassica napus L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2012Article
- Genetic mapping of new seed-expressed polyphenol oxidase genes in wheat (Triticum aestivum L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2012Article
- Alternative splicing in the coding region of Ppo-A1 directly influences the polyphenol oxidase activity in common wheat (Triticum aestivum L.).Functional & integrative genomics · 2011Article
- Duplicate polyphenol oxidase genes on barley chromosome 2H and their functional differentiation in the phenol reaction of spikes and grains.Journal of experimental botany · 2010Article
- Functional analysis of polyphenol oxidases by antisense/sense technology.Molecules (Basel, Switzerland) · 2007Review
- High-resolution mapping of the Alp locus and identification of a candidate gene HvMATE controlling aluminium tolerance in barley (Hordeum vulgare L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2007Article
- Allelic variation of polyphenol oxidase (PPO) genes located on chromosomes 2A and 2D and development of functional markers for the PPO genes in common wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2007Article
- A high-density consensus map of barley linking DArT markers to SSR, RFLP and STS loci and agricultural traits.BMC genomics · 2006Article
Corrections and comments
- Erratum issuedMatin, Peter [corrected to Martin, Peter]
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polyphenol oxidases (PPOs) are involved in the time-dependent darkening and discolouration of Asian noodles and other wheat end products. In this study, a doubled haploid (DH) population derived from Chara (moderately high PPO activity)/WW2449 (low PPO activity) was screened for PPO activity based on L-DOPA and L-tyrosine assays using whole seeds. Both these assays were significantly genetically correlated (r = 0.91) in measuring the PPO activity in this DH population. Quantitative trait loci (QTLs) analysis utilising a skeleton map enabled us to identify a major QTL controlling PPO activity based on L-DOPA and L-tyrosine on the long arm of chromosome 2A. The simple sequence repeat (SSR) marker GWM294b explained over 82% of the line mean phenotypic variation from samples collected in both 2000 and 2003. Four SSR markers were validated for PPO linkage in genetically diverse backgrounds and proven to correctly predict the PPO activity in more than 92% of wheat lines. Physical mapping using deletion lines of Chinese Spring has confirmed the location of the GWM294b, GWM312 and WMC170 on chromosome 2AL, between deletion breakpoints 2AL-C to 0.85. In order to identify functional gene markers, data searches for alignments between rice BAC/PAC clones assembled on chromosome 1 and 4, chromosome 7, and (1) the wheat expressed sequence tags mapped in deletion bin (2AL-C to 0.85) and (2) the coding sequence of a previously cloned wheat PPO gene were made and found significant sequence similarities with the PPO gene or common central domain of tyrosinase. Available PPO gene sequences in the National Centre for Biotechnology Information (NCBI) database have revealed that there is a significant molecular diversity at the nucleotide and amino acid level in the wheat PPO genes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.