ReviewNaunyn-Schmiedeberg's archives of pharmacology2005
TRP channels in airway smooth muscle as therapeutic targets.
Review in Naunyn-Schmiedeberg's archives of pharmacology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 39 citations in OpenAlex.
- Association of Serum Calcium with the Risk of Chronic Obstructive Pulmonary Disease: A Prospective Study from UK Biobank.Nutrients · 2023Article
- Roles of airway smooth muscle dysfunction in chronic obstructive pulmonary disease.Journal of translational medicine · 2018Review
- Voltage effects on muscarinic acetylcholine receptor-mediated contractions of airway smooth muscle.Physiological reports · 2018Article
- NaFrontiers in pharmacology · 2018Article
- Role of transient receptor potential vanilloid 1 in the modulation of airway smooth muscle tone and calcium handling.American journal of physiology. Lung cellular and molecular physiology · 2017Article
- Article
- Airway Smooth Muscle Sensitivity to Methacholine in Precision-Cut Lung Slices (PCLS) from Ovalbumin-induced Asthmatic Mice.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2015Article
- TRPC3 regulates release of brain-derived neurotrophic factor from human airway smooth muscle.Biochimica et biophysica acta · 2013Article
- Effects of ginger and its constituents on airway smooth muscle relaxation and calcium regulation.American journal of respiratory cell and molecular biology · 2013Article
- Ion channel regulation of intracellular calcium and airway smooth muscle function.Pulmonary pharmacology & therapeutics · 2009Review
- Airway smooth muscle as a target of asthma therapy: history and new directions.Respiratory research · 2006Review
- Transient receptor potential (TRP) channels as drug targets.Naunyn-Schmiedeberg's archives of pharmacology · 2006Article
- Small molecule vanilloid TRPV1 receptor antagonists approaching drug status: can they live up to the expectations?Naunyn-Schmiedeberg's archives of pharmacology · 2006Review
- The light-activated signaling pathway in SCN-projecting rat retinal ganglion cells.The European journal of neuroscience · 2006Article
- Determining the functional role of TRPC channels in primary cells.Pflugers Archiv : European journal of physiology · 2005Article
- TRP channels as new pharmacological targets.Naunyn-Schmiedeberg's archives of pharmacology · 2005Article
- Structure-function analysis of TRPV channels.Naunyn-Schmiedeberg's archives of pharmacology · 2005Review
- Functional characterization and physiological relevance of the TRPC3/6/7 subfamily of cation channels.Naunyn-Schmiedeberg's archives of pharmacology · 2005Review
- Regulation of TRPM2 channels in neutrophil granulocytes by ADP-ribose: a promising pharmacological target.Naunyn-Schmiedeberg's archives of pharmacology · 2005Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cation channels are of fundamental importance in regulating the function of airway smooth cells especially bronchoconstriction in response to spasmogens, and are therefore key players in the pathogenesis of asthma. To date, the identity of these cation channels remains a mystery. However, the recently emerged transient receptor potential (TRP) cation channel family has provided several promising channel candidates. The identification of the key TRP channels involved in regulating airway smooth muscle contractility, and therefore airway tone, could provide new and exciting prospects for the development of novel therapies for the treatment of airway diseases such as asthma.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.