Evidence map›Paper›PMID 15912884›Full record

ReviewBrain pathology (Zurich, Switzerland)2005

New roles for galectins in brain tumors--from prognostic markers to therapeutic targets.

Brianna N Stillman, Paul S Mischel, Linda G Baum

Open access · greenAbstract readReview
In one paragraph

Review in Brain pathology (Zurich, Switzerland), 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Review
  3. Galectin-1: a biomarker of surgical stress in murine model of cardiac surgery.International journal of clinical and experimental pathology · 2015
    Article
  4. Article
  5. Galectins and gliomas.Brain pathology (Zurich, Switzerland) · 2010
    Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Brianna N StillmanDepartment of Pathology and Laboratory Medicine and the Jonsson Comprehensive Cancer Center, UCLA School of Medicine, Los Angeles, California 90095, USA.
Paul S Mischel
Linda G Baum
Comprehensive Cardiovascular · US

Funding

A Novel Cell Death Pathway Induced by Galectin-1R01GM063281 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BAUM, LINDA G · 2001 to 2004
$1.0M
NIGMS NIH HHS R01 GM63281
6 · The paper itself

Abstract

Despite advances in diagnosis and treatment, brain tumors continue to be the leading cause of cancer-related death in patients under 35 years of age, demonstrating the need for better prognostic and therapeutic targets. Galectins, a family of mammalian carbohydrate binding proteins, are involved in many processes important for tumor survival and dissemination, including proliferation, apoptosis, transcriptional regulation, intracellular signaling, cell adhesion, and cell migration. Several galectins are expressed in human brain, with many galectins demonstrating altered expression during tumor progression. Thus, galectins and the functions regulated by this family of proteins are potential targets for the diagnosis and treatment of brain cancer. This review highlights the roles of galectins in cancer and specifically, the developing field of galectins in brain cancer.

Indexed as

Biomarkers, TumorAnimalsBrain NeoplasmsGalectinsHumansPrognosisBiomarkers, TumorGalectins

Identifiers

PMID15912884
PMCPMC8095905
OpenAlexW2088283739

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.