ArticleAnnals of surgery2005
Analysis of long-term outcomes of 3200 liver transplantations over two decades: a single-center experience.
Article in Annals of surgery, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 95 papers.
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Who cites it
95 citing papers in PubMed, 405 citations in OpenAlex.
- An evaluation of the safety and preliminary efficacy of peri- and post-operative treprostinil in preventing ischemia and reperfusion injury in adult orthotopic liver transplant recipients.Clinical transplantation · 2021Trial
- Posttransplant muscle mass measured by urinary creatinine excretion rate predicts long-term outcomes after liver transplantation.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2019Trial
- Celsior versus University of Wisconsin preserving solutions for liver transplantation: postreperfusion syndrome and outcome of a 5-year prospective randomized controlled study.World journal of surgery · 2011Trial
- Socio-Occupational Aspects in Liver Transplant Candidates and Recipients: A Retrospective Cohort Study.Journal of occupational rehabilitation · 2026Article
- Differences in Mortality by Donor Sex and Age in a Multinational Cohort of Liver Transplant Recipients.Transplantation direct · 2026Article
- A 23-Year Comprehensive Analysis of over 4000 Liver Transplants in Türkiye: Integrating Clinical Outcomes with Public Health Insights.Healthcare (Basel, Switzerland) · 2026Article
- Shortening the recipient warm ischemia time could be a strategy for expanding the liver donor pool.World journal of gastroenterology · 2025Article
- Recipient warm ischemic time negatively influences biliary complications and graft survival - a single center retrospective analysis.Frontiers in gastroenterology (Lausanne, Switzerland) · 2025Article
- Staged preoperative evaluation of potential living donors for liver transplantation.Translational gastroenterology and hepatology · 2025Article
- Key challenges of post-liver transplant weight management.World journal of transplantation · 2024Review
- Impact of Donor Obesity on Graft and Recipient Survival Outcomes After Liver Transplantation: A Systematic Review and Meta-analysis.Transplantation direct · 2024Article
- National Trends in Utilization of Normothermic Machine Perfusion in DCD Liver Transplantation.Transplantation direct · 2024Article
- Pediatric and adult liver transplantation in Bahrain: The experiences in a country with no available liver transplant facilities.World journal of transplantation · 2024Article
- Review
- LIVER RETRANSPLANTATION: PROGNOSTIC SCORES AND RESULTS IN THE STATE OF PARANÁ.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2024Article
- Article
- A bibliometric and visualized analysis of hepatic ischemia-reperfusion injury (HIRI) from 2002 to 2021.Heliyon · 2023Article
- Early postoperative duplex ultrasound findings of the hepatic artery in postoperative vascular complications from paediatric liver transplantation.Journal of ultrasound · 2023Article
- Liver retransplants using living donors: An approach for management.Liver research (Beijing, China) · 2023Article
- Outcomes of Adult Liver Retransplantation: A Canadian National Database Analysis.Canadian journal of gastroenterology & hepatology · 2022Article
35 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
18 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveFew studies have evaluated long-term outcomes after orthotopic liver transplantation (OLT). This work analyzes the experience of nearly 2 decades by the same team in a single center. Outcomes of OLT and factors affecting survival were analyzed.
methodsRetrospective analysis of 3200 consecutive OLTs that were performed at our institution, between February 1984 and December 31, 2001.
resultsOf 2662 recipients, 578 (21.7%) and 659 (24.7%) were pediatric and urgent patients, respectively. Overall 1-, 5-, 10-, and 15-year patient and graft survival estimates were 81%, 72%, 68%, 64% and 73%, 64%, 59%, 55%, respectively. Patient survival significantly improved in the second (1992-2001) versus the era I (1984-1991) of transplantation (P < 0.001). Similarly, graft survival was better in the era II of transplantation (P < 0.02). However, biliary and infectious complications increased in era II. When OLT indications were considered, best recipient survival was obtained in children with biliary atresia (82%, 79%, and 78% at 1, 5, and 10 years, respectively), while malignant disease in adult patients resulted in the worst outcomes of 68% and 43% at 1 and 5 years, post-OLT. Further, patients <18 years and nonurgent recipients exhibited superior survival when compared with recipients >18 years (P < 0.001) or urgent patients (P < 0.001). Of 13 donor and recipient variables, era of OLT, recipient age, urgent status, donor age, donor length of hospital stay, etiology of liver disease, retransplantation, warm and cold ischemia, but not graft type (whole, split, living-donor), significantly impacted patient survival.
conclusionsLong-term benefits of OLT are greatest in pediatric and nonurgent patients. Multiple factors involving the recipient, etiology of liver disease, donor characteristics, operative variables, and surgical experience influence long-term survival outcomes. By balancing and matching these factors with a given recipient, optimum results can be achieved.
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