ArticleAnnals of surgery2005
When fundoplication fails: redo?
Article in Annals of surgery, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 6 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
63 citing papers in PubMed, 6 syntheses or guidelines pooled it, 192 citations in OpenAlex.
- Management of recurrent hiatal hernia: a systematic review and meta-analysis comparing mesh versus no mesh reinforcement.Hernia : the journal of hernias and abdominal wall surgery · 2025Pooled it
- Pediatric Gastroesophageal Reflux Clinical Practice Guidelines: Joint Recommendations of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition.Journal of pediatric gastroenterology and nutrition · 2018Guideline
- Laparoscopic fundoplication surgery versus medical management for gastro-oesophageal reflux disease (GORD) in adults.The Cochrane database of systematic reviews · 2015Pooled it
- A comprehensive review of laparoscopic redo fundoplication.Surgical endoscopy · 2011Pooled it
- Treatment for Barrett's oesophagus.The Cochrane database of systematic reviews · 2010Pooled it
- Surgical reintervention after failed antireflux surgery: a systematic review of the literature.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2009Pooled it
- Endoscopic full-thickness plication versus laparoscopic fundoplication: a prospective study on quality of life and symptom control.Surgical endoscopy · 2012Trial
- Endoscopic ultrasound for the evaluation of Nissen fundoplication integrity: a blinded comparison with conventional testing.Surgical endoscopy · 2007Trial
- Symmetrical anterior-posterior partial fundoplication: technique and outcomes.Surgical endoscopy · 2026Article
- Clinical and computed tomography outcome after primary and revisional fundoplication.Surgical endoscopy · 2026Observational
- Gastrointestinal Complaints After Fundoplication: Rapid Review and Evidence Mapping.Current gastroenterology reports · 2026Review
- Analysis of outcomes of reoperative fundoplication in more than 500 patients after failed primary antireflux surgery: Experience over two decades.The Journal of thoracic and cardiovascular surgery · 2025Article
- Utility of pH monitoring in surgical decision-making and outcome prediction in revisional antireflux surgery for anatomical failure.Surgical endoscopy · 2025Article
- Computed tomography roadmap for post-operative fundoplication imaging with a novel structured reporting checklist.Journal of minimal access surgery · 2025Article
- Patient reported outcomes and decision regret scores in redo-paraesophageal hernia repair.Surgical endoscopy · 2025Article
- The impact of obesity on gastroesophageal reflux disease recurrence following re-operative anti-reflux surgery.Surgical endoscopy · 2024Article
- Long-term results after laparoscopic revision fundoplication: a retrospective, single-center analysis in 194 patients with recurrent hiatal hernia.Esophagus : official journal of the Japan Esophageal Society · 2024Article
- Current Status of Anti-Reflux Surgery as a Treatment for GERD.Medicina (Kaunas, Lithuania) · 2024Review
- Additional fundophrenicopexia, after Nissen fundoplication, reduces postoperative dysphagia and re-operation rate in the long-term follow up.Surgical endoscopy · 2022Article
- Minimally Invasive Abdominal Repair of a Giant Paraesophageal Hiatal Hernia with Occupation of the Right Thorax in a 53-Year-Old Man.Case reports in surgery · 2022Article
3 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe largest series in the literature dealing with redo fundoplication was presented and published in 1999 and included 100 patients. Herein we update this initial series of 100, with 207 additional patients who have undergone redo fundoplication (n = 307). SUMMARY BACKGROUND DATA: Increasing numbers of patients are failing esophagogastric fundoplication and requiring redo procedures. Data regarding the nature of these failures have been scant.
methodsData on all patients undergoing foregut surgery are collected prospectively. Between 1991 and 2004, 307 patients underwent redo fundoplication for the management of anatomic complications or recurrent GERD. Statistical analysis was performed with multiple chi2 and Mann-Whitney U analyses, as well as ANOVA.
resultsBetween 1991 and 2004, 1892 patients underwent primary fundoplication for GERD (1734) or paraesophageal hernia (158). Of these, 54 required redo fundoplication (2.8%). The majority of failures (73%) were managed within 2 years of the initial operation (P = 0.0001). The mechanism of failure was transdiaphragmatic wrap herniation in 33 of 54 (61%). In the 231 patients who underwent fundoplication elsewhere, 109 had transdiaphragmatic herniation (47%, P = NS). In this group of 285 patients, 22 (8%) required another redo (P = NS). The majority of the procedures were initiated laparoscopically (240/307, 78%), with 20 converted (8%). Overall mortality was 0.3%.
conclusionsFailure of fundoplication is unusual in experienced hands. Most are managed within 2 years of the initial operation. Wrap herniation has now become the most common mechanism of failure requiring redo. Redo fundoplication was successful in 93% of patients, and most could be safely handled laparoscopically.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.