ArticleGenetics2005
On the evolutionary stability of Mendelian segregation.
Article in Genetics, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 44 citations in OpenAlex.
- A selfish supergene causes meiotic drive through both sexes inProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Meiotic drive in chronic lymphocytic leukemia compared with other malignant blood disorders.Scientific reports · 2022Article
- Detection of sexually antagonistic transmission distortions in trio datasets.Evolution letters · 2022Article
- Influence of Gender Bias on Distribution of Hybrid Sterility in Rice.Frontiers in plant science · 2022Review
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- Inheritance of Susceptibility to Malignant Blood Disorders.Scientific reports · 2019Article
- Haploid selection, sex ratio bias, and transitions between sex-determining systems.PLoS biology · 2018Article
- Modeling the Evolution of Female Meiotic Drive in Maize.G3 (Bethesda, Md.) · 2018Article
- Haploid Selection Favors Suppressed Recombination Between Sex Chromosomes Despite Causing Biased Sex Ratios.Genetics · 2017Article
- Evolutionary mysteries in meiosis.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2016Review
- On the origin of sex chromosomes from meiotic drive.Proceedings. Biological sciences · 2015Article
- Specialists and generalists: the sexual ecology of the genome.Cold Spring Harbor perspectives in biology · 2014Review
- Article
- Social dilemmas among supergenes: intragenomic sexual conflict and a selfing solution in Oenothera.Evolution; international journal of organic evolution · 2011Article
- Segregation distortion causes large-scale differences between male and female genomes in hybrid ants.Proceedings of the National Academy of Sciences of the United States of America · 2010Article
- The evolution of sex-independent transmission ratio distortion involving multiple allelic interactions at a single locus in rice.Genetics · 2008Article
- Possible imprinting and microchimerism in chronic lymphocytic leukemia and related lymphoproliferative disorders.Translational oncogenomics · 2008Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We present a model of a primary locus subject to viability selection and an unlinked locus that causes sex-specific modification of the segregation ratio at the primary locus. If there is a balanced polymorphism at the primary locus, a population undergoing Mendelian segregation can be invaded by modifier alleles that cause sex-specific biases in the segregation ratio. Even though this effect is particularly strong if reciprocal heterozygotes at the primary locus have distinct viabilities, as might occur with genomic imprinting, it also applies if reciprocal heterozygotes have equal viabilities. The expected outcome of the evolution of sex-specific segregation distorters is all-and-none segregation schemes in which one allele at the primary locus undergoes complete drive in spermatogenesis and the other allele undergoes complete drive in oogenesis. All-and-none segregation results in a population in which all individuals are maximally fit heterozygotes. Unlinked modifiers that alter the segregation ratio are unable to invade such a population. These results raise questions about the reasons for the ubiquity of Mendelian segregation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.