Evidence map›Paper›PMID 15910681›Full record

ArticleBMC bioinformatics2005

arrayCGHbase: an analysis platform for comparative genomic hybridization microarrays.

Björn Menten, Filip Pattyn, Katleen De Preter, Piet Robbrecht, Evi Michels, Karen Buysse, Geert Mortier, Anne De Paepe, Steven van Vooren, Joris Vermeesch and 5 more

Abstract read
In one paragraph

Article in BMC bioinformatics, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
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  8. Sertoli Cell-Only Syndrome: Behind the Genetic Scenes.BioMed research international · 2016
    Article
  9. Article
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  11. Redefining the MED13L syndrome.European journal of human genetics : EJHG · 2015
    Article
  12. Refinement of the critical 2p25.3 deletion region: the role of MYT1L in intellectual disability and obesity.Genetics in medicine : official journal of the American College of Medical Genetics · 2015
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Björn MentenCenter for Medical Genetics, Ghent University Hospital, De Pintelaan 185, B-9000 Ghent, Belgium. bjorn.menten@ugent.be <bjorn.menten@ugent.be>
Filip Pattyn
Katleen De Preter
Piet Robbrecht
Evi Michels
Karen Buysse
Geert Mortier
Anne De Paepe
Steven van Vooren
Joris Vermeesch
Yves Moreau
Bart De Moor
Stefan Vermeulen
Frank Speleman
Jo Vandesompele

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe availability of the human genome sequence as well as the large number of physically accessible oligonucleotides, cDNA, and BAC clones across the entire genome has triggered and accelerated the use of several platforms for analysis of DNA copy number changes, amongst others microarray comparative genomic hybridization (arrayCGH). One of the challenges inherent to this new technology is the management and analysis of large numbers of data points generated in each individual experiment.

resultsWe have developed arrayCGHbase, a comprehensive analysis platform for arrayCGH experiments consisting of a MIAME (Minimal Information About a Microarray Experiment) supportive database using MySQL underlying a data mining web tool, to store, analyze, interpret, compare, and visualize arrayCGH results in a uniform and user-friendly format. Following its flexible design, arrayCGHbase is compatible with all existing and forthcoming arrayCGH platforms. Data can be exported in a multitude of formats, including BED files to map copy number information on the genome using the Ensembl or UCSC genome browser.

conclusionArrayCGHbase is a web based and platform independent arrayCGH data analysis tool, that allows users to access the analysis suite through the internet or a local intranet after installation on a private server. ArrayCGHbase is available at http://medgen.ugent.be/arrayCGHbase/.

Indexed as

Base SequenceChromosomesComputational BiologyComputer GraphicsDatabase Management SystemsDatabases, GeneticGene Expression ProfilingGenes, NeoplasmGenes, ReporterGenome, HumanGenomicsHumansInformation Storage and RetrievalInternetNeoplasmsNucleic Acid Hybridization

Identifiers

PMID15910681
PMCPMC1173083

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.