ReviewCurrent pain and headache reports2005
Migraine genetics: an update.
Review in Current pain and headache reports, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Migraine is a dysfunction of neuronal potassium ion channels.Frontiers in neurology · 2025Review
- The Dawn and Advancement of the Knowledge of the Genetics of Migraine.Journal of clinical medicine · 2024Review
- Synaptic alterations in visual cortex reshape contrast-dependent gamma oscillations and inhibition-excitation ratio in a genetic mouse model of migraine.The journal of headache and pain · 2022Article
- Migraine: Calcium Channels and Glia.International journal of molecular sciences · 2021Review
- Calcium Channel Splice Variants and Their Effects in Brain and Cardiovascular Function.Advances in experimental medicine and biology · 2021Article
- A novel de novo mutation in ATP1A3 and childhood-onset schizophrenia.Cold Spring Harbor molecular case studies · 2016Article
- A missense variant of the ATP1A2 gene is associated with a novel phenotype of progressive sensorineural hearing loss associated with migraine.European journal of human genetics : EJHG · 2015Article
- Calcium channels and synaptic transmission in familial hemiplegic migraine type 1 animal models.Biophysical reviews · 2014Review
- CaV2.1 channelopathies.Pflugers Archiv : European journal of physiology · 2010Review
- A migraine variant with abdominal colic and Alice in Wonderland syndrome: a case report and review.BMC neurology · 2010Review
- Novel mutations affecting the Na, K ATPase alpha model complex neurological diseases and implicate the sodium pump in increased longevity.Human genetics · 2009Article
- Current migraine management - patient acceptability and future approaches.Neuropsychiatric disease and treatment · 2008Article
- Genetics of migraine and pharmacogenomics: some considerations.The journal of headache and pain · 2007Review
- The cerebellum and migraine.Headache · 2007Review
- Familial hemiplegic migraine.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2007Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A growing interest in genetic research in migraine has resulted in the identification of several chromosomal regions that are involved in migraine. However, the identification of mutations in the genes for familial hemiplegic migraine (FHM) forms the only true molecular genetic knowledge of migraine thus far. The increased number of mutations in the FHM1 (CACNA1A) and the FHM2 (ATP1A2) genes allow studying the relationship between genetic findings in both genes and the clinical features in patients. A wide spectrum of symptoms is seen in patients. Additional cerebellar ataxia and (childhood) epilepsy can occur in FHM1 and FHM2. Functional studies show a dysfunction in ion transport as the key factor in the pathophysiology of (familial hemiplegic) migraine that predict an increased susceptibility to cortical spreading depression--the underlying mechanism of migraine aura.
Indexed as
Identifiers
15907261What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.