Evidence map›Paper›PMID 15906755›Full record

Trial reportDigestive diseases and sciences2005

Efficacy of triple therapy plus cetraxate for the Helicobacter pylori eradication in partial gastrectomy patients.

Keisuke Kubota, Nobuyuki Shimizu, Koji Nozaki, Yutarou Takeshita, Tetsuya Ueda, Kazuhiro Imamura, Naoki Hiki, Hirokazu Yamaguchi, Shouji Shimoyama, Ken-Ichi MaFune and 1 more

Abstract readClinical TrialRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Digestive diseases and sciences, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Efficacy of a quadruple therapy regimen for Helicobacter pylori eradication after partial gastrectomy.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2016
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Keisuke KubotaDepartment of Gastrointestinal Surgery, The University of Tokyo, Tokyo, Japan. kubotak-dis@h.u-tokyo.ac.jp
Nobuyuki Shimizu
Koji Nozaki
Yutarou Takeshita
Tetsuya Ueda
Kazuhiro Imamura
Naoki Hiki
Hirokazu Yamaguchi
Shouji Shimoyama
Ken-Ichi MaFune
Michio Kaminishi
The University of Tokyo · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the present study, we aimed to establish an additional standardized protocol with a higher H. pylori eradication rate in the remnant stomach. Fifty-five H. pylori-positive patients were randomly allocated to one of three regimens: LAC--lansoprazole, amoxicillin, and clarithromycin b.i.d. for 7 days (n = 17); LAC+CET--LAC b.i.d. plus cetraxate q.i.d. for 7 days (n = 20); and LEFT--LAC for 7 days in a horizontal body position on the left side for 30 min (n = 18). Patient compliance and side effects were checked via interviews. H. pylori eradication was successful in 75, 72, and 41% in LAC+CET, LEFT, and LAC, respectively. The eradication rate was significantly higher in LAC+CET than in LAC (P = 0.024) but not in LEFT (P = 0.058). Adverse events that occurred in each group were almost all mild ones. Cetraxate plus LAC for 1 week is a safe and effective regime for the eradication of H. pylori in patients after partial gastrectomy.

Indexed as

Gastric StumpHelicobacter pylori2-PyridinylmethylsulfinylbenzimidazolesAdultAgedAnti-Infective AgentsAnti-Ulcer AgentsDrug Administration ScheduleDrug Therapy, CombinationFemaleGastrectomyHelicobacter InfectionsHumansLansoprazoleMaleMiddle Aged2-PyridinylmethylsulfinylbenzimidazolesAnti-Infective AgentsAnti-Ulcer AgentscetraxateLansoprazoleOmeprazoleTranexamic Acid

Identifiers

PMID15906755
OpenAlexW1999508368

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.