ReviewNaunyn-Schmiedeberg's archives of pharmacology2005
Receptor-operated cation channels formed by TRPC4 and TRPC5.
Review in Naunyn-Schmiedeberg's archives of pharmacology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed.
- Cannabidiol and other non-psychotropic cannabinoids from Cannabis sativa as therapeutics for microglial-mediated neuroinflammation and neurodegeneration.Journal of cannabis research · 2026Review
- A bibliometric study of the most-cited research articles and reviews in Naunyn-Schmiedeberg's Archives of Pharmacology (1969-2024).Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- TRPC4/5 inhibitors: Phase I results and proof of concept studies.European archives of psychiatry and clinical neuroscience · 2025Review
- Interactions between the Polysialylated Neural Cell Adhesion Molecule and the Transient Receptor Potential Canonical Channels 1, 4, and 5 Induce Entry of CaInternational journal of molecular sciences · 2022Article
- Involvement of TRPC5 channels, inwardly rectifying KThe Journal of physiology · 2021Article
- Emerging role of transient receptor potential (TRP) channels in cancer progression.BMB reports · 2020Review
- TRPC1 Regulates the Activity of a Voltage-Dependent Nonselective Cation Current in Hippocampal CA1 Neurons.Cells · 2020Article
- Differential PI(4,5)PScientific reports · 2019Article
- Redox regulation of transient receptor potential channels in the endothelium.Microcirculation (New York, N.Y. : 1994) · 2017Review
- Smooth Muscle Ion Channels and Regulation of Vascular Tone in Resistance Arteries and Arterioles.Comprehensive Physiology · 2017Review
- Molecular Determinants of the Sensitivity to Gq/11-Phospholipase C-dependent Gating, Gd3+ Potentiation, and Ca2+ Permeability in the Transient Receptor Potential Canonical Type 5 (TRPC5) Channel.The Journal of biological chemistry · 2017Article
- Electrophysiological Signature of Homomeric and Heteromeric Glycine Receptor Channels.The Journal of biological chemistry · 2016Article
- Critical roles of Gi/o proteins and phospholipase C-δ1 in the activation of receptor-operated TRPC4 channels.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Low K⁺ current in arterial myocytes with impaired K⁺-vasodilation and its recovery by exercise in hypertensive rats.Pflugers Archiv : European journal of physiology · 2014Article
- G protein-coupled receptor signalling potentiates the osmo-mechanical activation of TRPC5 channels.Pflugers Archiv : European journal of physiology · 2014Article
- Dual depolarization responses generated within the same lateral septal neurons by TRPC4-containing channels.Pflugers Archiv : European journal of physiology · 2014Article
- Store-operated Ca2+ entry does not control proliferation in primary cultures of human metastatic renal cellular carcinoma.BioMed research international · 2014Article
- Article
- Molecular mechanism of TRP channels.Comprehensive Physiology · 2013Review
- Phospholipase C not protein kinase C is required for the activation of TRPC5 channels by cholecystokinin.European journal of pharmacology · 2012Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
TRPC4 and TRPC5 form cation channels that contribute to phospholipase C-dependent Ca(2+) entry following stimulation of G-protein-coupled receptors or receptor tyrosine kinases. Surprisingly, in different studies, TRPC4 and TRPC5 have been shown to form either store-operated channels with a relatively high Ca(2+) permeability, or nonselective cation channels activated independently of store depletion. In this review, we summarize and discuss data on the regulation and permeability properties of TRPC4 and TRPC5, and data on native channels that might be composed of these isoforms.
Indexed as
Identifiers
15902430What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.