Further evidence that germline CEBPA mutations cause dominant inheritance of acute myeloid leukaemia.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

31 citing papers in PubMed, 76 citations in OpenAlex.

1. Genomic analysis of germ line and somatic variants in familial myelodysplasia/acute myeloid leukemia.Blood · 2015
   Trial
2. Cytoplasmic retention of IRF3 binding Vimentin competitively with ERK1/2 mitigates acute myeloid leukemia through TFEB nuclear translocation.Cell communication and signaling : CCS · 2026
   Article
3. Sporadic and Familial Acute Myeloid Leukemia with CEBPA Mutations.Current hematologic malignancy reports · 2023
   Review
4. Location, location, location: A mini-review ofLeukemia research reports · 2023
   Review
5. Clinical considerations at the intersection of hematopoietic cell transplantation and hereditary hematopoietic malignancy.Frontiers in oncology · 2023
   Review
6. New progress in the study of germline susceptibility genes of myeloid neoplasms.Oncology letters · 2021
   Review
7. [Investigation and clinical analysis of a family with germline CEBPA mutations in acute myeloid leukemia].Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi · 2020
   Article
8. Secondary leukemia in patients with germline transcription factor mutations (RUNX1, GATA2, CEBPA).Blood · 2020
   Review
9. Genetic Predisposition to Myelodysplastic Syndrome in Clinical Practice.Hematology/oncology clinics of North America · 2020
   Review
10. The complex genetic landscape of familial MDS and AML reveals pathogenic germline variants.Nature communications · 2020
    Article
11. Female reproductive potential after oncological treatment: a rare case report of acute myeloid leukemia in monozygotic twin sisters with literature review.Journal of ovarian research · 2020
    Review
12. Identification of novel CEBPA double mutations capable of promoting familial AML via the suppression of myeloid differentiation.American journal of translational research · 2020
    Article
13. Transcription factor mutations as a cause of familial myeloid neoplasms.The Journal of clinical investigation · 2019
    Review
14. Hematological Malignancies in Adults With a Family Predisposition.Deutsches Arzteblatt international · 2018
    Review
15. NR4A1 and NR4A3 restrict HSC proliferation via reciprocal regulation of C/EBPα and inflammatory signaling.Blood · 2018
    Article
16. Index case of acute myeloid leukemia in a family harboring a novelBlood advances · 2017
    Article
17. Preleukemia: one name, many meanings.Leukemia · 2017
    Review
18. Whole exome sequencing reveals a C-terminal germline variant in CEBPA-associated acute myeloid leukemia: 45-year follow up of a large family.Haematologica · 2016
    Article
19. Genetic predispositions to childhood leukemia.Therapeutic advances in hematology · 2013
    Article
20. Concordant acute myeloblastic leukemia in monozygotic twins with germline and shared somatic mutations in the gene for CCAAT-enhancer-binding protein α with 13 years difference at onset.Haematologica · 2013
    Article

Corrections and comments

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Authors and funding

5 authors at 1 institution in 1 country.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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