ArticleBiology of reproduction2005
Demonstration of a glycoprotein derived from the Ceacam10 gene in mouse seminal vesicle secretions.
Article in Biology of reproduction, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 27 citations in OpenAlex.
- Physiological functions of seminal vesicle secretions in male fertility.Histology and histopathology · 2026Review
- Effect of autophagy-related (Atg) protein 5 on mouse epididymal sperm maturation.Journal of assisted reproduction and genetics · 2026Article
- Seminal Vesicle-Derived Exosomes for the Regulation of Sperm Activity.Advances in anatomy, embryology, and cell biology · 2026Review
- Multiple transcriptome analyses reveal mouse testis developmental dynamics.BMC genomics · 2024Article
- Polarized epithelium-sperm co-culture system reveals stimulatory factors for the secretion of mouse epididymal quiescin sulfhydryl oxidase 1.The Journal of reproduction and development · 2022Article
- Secretory mouse quiescin sulfhydryl oxidase 1 aggregates defected human and mouse spermatozoa in vitro and in vivo.iScience · 2021Article
- The polycomb group protein PCGF6 mediates germline gene silencing by recruiting histone-modifying proteins to target gene promoters.The Journal of biological chemistry · 2020Article
- Genetic Factors Influencing Sperm Competition.Frontiers in genetics · 2019Review
- Socially cued seminal fluid gene expression mediates responses in ejaculate quality to sperm competition risk.Proceedings. Biological sciences · 2017Article
- Identification, characterization and purification of porcine Quiescin Q6-Sulfydryl Oxidase 2 protein.BMC veterinary research · 2017Article
- Roles of the reproductive tract in modifications of the sperm membrane surface.The Journal of reproduction and development · 2016Review
- Sperm competition risk drives plasticity in seminal fluid composition.BMC biology · 2015Article
- Heterogenous turnover of sperm and seminal vesicle proteins in the mouse revealed by dynamic metabolic labeling.Molecular & cellular proteomics : MCP · 2012Article
- Comparative proteomic analysis of proteins involved in the tumorigenic process of seminal vesicle carcinoma in transgenic mice.International journal of proteomics · 2010Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
CEACAM10 was purified from mouse seminal vesicle secretions by a series of purification steps that included ion exchange chromatography on a DEAE-Sephacel column and ion exchange high-performance liquid chromatography on a sulfopropyl column. It was shown to be a 36-kDa glycoprotein with an N-linked carbohydrate moiety. The circular dichromoism spectrum of CEACAM10 in 50 mM phosphate buffer at pH 7.4 appeared as one negative band arising from the beta form at 217 nm. CEACAM10 was expressed predominantly in seminal vesicles of adult mice. Both CEACAM10 and its mRNA were demonstrated on the luminal epithelium of the mucosal folds in the seminal vesicle. The amount of Ceacam10 mRNA in the seminal vesicle was correlated with the stage of animal maturation. Castration of adult mice resulted in cessation of Ceacam10 expression, while treatment of castrated mice with testosterone propionate in corn oil restored Ceacam10 expression in the seminal vesicle. During the entire course of pregnancy, Ceacam10 might be silent in the embryo. A cytochemical study illustrated the presence of the CEACAM10 binding region on the entire surface of mouse sperm. CEACAM10-sperm binding greatly enhanced sperm motility in vitro.
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