ArticleJournal of comparative physiology. B, Biochemical, systemic, and environmental physiology2005
Characterization of single L-type Ca2+ channels in myocytes isolated from the cricket lateral oviduct.
Article in Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Intermediate conductance CaFrontiers in insect science · 2022Article
- BK Channels Are Activated by Functional Coupling With L-Type CaFrontiers in insect science · 2021Article
- Calcium-dependent control of temporal processing in an auditory interneuron: a computational analysis.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2010Article
Corrections and comments
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Authors and funding
2 authors.
Funding
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Abstract
The single Ca2+ channel activity was obtained from cell-attached patch recordings with the use of pipettes filled with 100 mM Ba2+ as the charge carrier in myocytes isolated from the lateral oviduct of cricket Gryllus bimaculatus. The following results were obtained. (1) The channel had a unitary conductance of 18 pS. (2) The open time histogram of the channel could be fitted with a single exponential while the closed time histogram could be fitted with the sum of two exponentials, suggesting that there are at least one open state and two closed states for this channel. (3) The open probability of the channel increased with increasing membrane depolarization. (4) The mean current reconstructed by averaging individual current trace responses inactivated slowly and the current-voltage relationship for the peak mean current showed a bell-shaped relation. (5) The dihydropyridine (DHP) Ca2+ antagonist, nifedipine, reduced the mean current by increasing the proportion of "blank" sweeps. On the other hand, the DHP Ca2+ agonist, Bay K 8644, increased the mean current by increasing the mean open-times of the channel. These results confirm a presence of DHP-sensitive L-type Ca2+ channel in myocytes isolated from the lateral oviduct of cricket G. bimaculatus.
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Registered trials
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