ReviewNeuroRx : the journal of the American Society for Experimental NeuroTherapeutics2005
Magnetic resonance imaging, microscopy, and spectroscopy of the central nervous system in experimental animals.
Review in NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 65 citations in OpenAlex.
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- Multimodal imaging of hair follicle bulge-derived stem cells in a mouse model of traumatic brain injury.Cell and tissue research · 2020Article
- Retinal and Cortical Blood Flow Dynamics Following Systemic Blood-Neural Barrier Disruption.Frontiers in neuroscience · 2017Article
- Neuroradiological evaluation of demyelinating disease.Therapeutic advances in neurological disorders · 2013Article
- Imaging of cells and nanoparticles: implications for drug delivery to the brain.Pharmaceutical research · 2012Review
- Preclinical (1)H-MRS neurochemical profiling in neurological and psychiatric disorders.Bioanalysis · 2012Review
- MRI in rodent models of brain disorders.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2011Review
- Neuropathological differences between rats and mice after spinal cord injury.Journal of magnetic resonance imaging : JMRI · 2010Article
- Deep gray matter T2 hypointensity correlates with disability in a murine model of MS.Journal of the neurological sciences · 2009Article
- Inflammation on the mind: visualizing immunity in the central nervous system.Current topics in microbiology and immunology · 2009Review
- Acute hemorrhagic demyelination in a murine model of multiple sclerosis.Journal of neuroinflammation · 2008Article
- Facilitating the development of controlled vocabularies for metabolomics technologies with text mining.BMC bioinformatics · 2008Article
- Neuroimaging: anything to do with neurotherapeutics?NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics · 2005Article
- Single-photon emission computed tomography in neurotherapeutics.NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics · 2005Review
- Imaging of multiple sclerosis: role in neurotherapeutics.NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics · 2005Review
- Neuroimaging in traumatic brain imaging.NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics · 2005Review
- Whole animal imaging.Wiley interdisciplinary reviews. Systems biology and medicineReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
Over the last two decades, microscopic resolution in vivo magnetic resonance imaging (MRI) techniques have been developed and extensively used in the study of animal models of human diseases. Standard MRI methods are frequently used in clinical studies and in the general clinical practice of human neurological diseases. This generates a need for similar studies in experimental animal research. Because small rodents are the most commonly used species as animal models of neurological diseases, the MRI techniques need to be able to provide microscopic resolution and high signal-to-noise ratio images in relatively short time. Small animal MRI systems use very high field-strength magnets, which results in higher signal to noise ratio; however, the contrast characteristics of live tissue are different at these field strengths. In addition to standard MRI techniques, several new applications have been implemented in experimental animals, including diffusion and perfusion studies, MR angiography, functional MRI studies, MRI tractography, proton and phosphorous spectroscopy, cellular and molecular imaging using novel contrast methods. Here we give an overview of how to establish a small animal imaging facility with the goal of CNS imaging. We describe the basic physical processes leading to MR signal generation, highlighting the differences between standard clinical MRI and small animal MRI. Finally, typical findings in the most common neurological disease categories and novel MRI/magnetic resonance spectroscopy methods used in their study are also described.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.