ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2005
Diversity and redundancy in bacterial chromosome segregation mechanisms.
Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Chromosome remodelling by SMC/Condensin inProceedings of the National Academy of Sciences of the United States of America · 2022Article
- Maintenance of multipartite genome system and its functional significance in bacteria.Journal of genetics · 2018Review
- Unique Function of the Bacterial Chromosome Segregation Machinery in Apically Growing Streptomyces - Targeting the Chromosome to New Hyphal Tubes and its Anchorage at the Tips.PLoS genetics · 2016Article
- Characterization of chromosomal and megaplasmid partitioning loci in Thermus thermophilus HB27.BMC genomics · 2015Article
- Structure and DNA-binding properties of the Bacillus subtilis SpoIIIE DNA translocase revealed by single-molecule and electron microscopies.Nucleic acids research · 2014Article
- The Toxoplasma gondii kinetochore is required for centrosome association with the centrocone (spindle pole).Cellular microbiology · 2014Article
- The chromosome cycle of prokaryotes.Molecular microbiology · 2013Review
- Genetic interactions of smc, ftsK, and parB genes in Streptomyces coelicolor and their developmental genome segregation phenotypes.Journal of bacteriology · 2009Article
- Escherichia coli low-copy-number plasmid R1 centromere parC forms a U-shaped complex with its binding protein ParR.Nucleic acids research · 2008Article
- Structural analysis of the ParR/parC plasmid partition complex.The EMBO journal · 2007Article
- Deletion of the parA (soj) homologue in Pseudomonas aeruginosa causes ParB instability and affects growth rate, chromosome segregation, and motility.Journal of bacteriology · 2007Article
- A dynamic, mitotic-like mechanism for bacterial chromosome segregation.Genes & development · 2006Article
- Entropy-driven spatial organization of highly confined polymers: lessons for the bacterial chromosome.Proceedings of the National Academy of Sciences of the United States of America · 2006Article
- Basic mechanism of eukaryotic chromosome segregation.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2005Review
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3 authors.
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Abstract
Bacterial cells are much smaller and have a much simpler overall structure and organization than eukaryotes. Several prominent differences in cell organization are relevant to the mechanisms of chromosome segregation, particularly the lack of an overt chromosome condensation/decondensation cycle and the lack of a microtubule-based spindle. Although bacterial chromosomes have a rather dispersed appearance, they nevertheless have an underlying high level of spatial organization. During the DNA replication cycle, early replicated (oriC) regions are localized towards the cell poles, whereas the late replicated terminus (terC) region is medially located. This spatial organization is thought to be driven by an active segregation mechanism that separates the sister chromosomes continuously as replication proceeds. Comparisons of various well-characterized bacteria suggest that the mechanisms of chromosome segregation are likely to be diverse, and that in many bacteria, multiple overlapping mechanisms may contribute to efficient segregation. One system in which the molecular mechanisms of chromosome segregation are beginning to be elucidated is that of sporulating cells of Bacillus subtilis. The key components of this system have been identified, and their functions are understood, in outline. Although this system appears to be specialized, most of the functions are conserved widely throughout the bacteria.
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