ArticlePlant physiology2005
Analysis of a sugar response mutant of Arabidopsis identified a novel B3 domain protein that functions as an active transcriptional repressor.
Article in Plant physiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.
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Who cites it
58 citing papers in PubMed, 126 citations in OpenAlex.
- A Wild Emmer Wheat B3 Transcription Factor Regulates Seed Growth and Nutrient Allocation.Plant, cell & environment · 2026Article
- Regulation of developmental transitions in plants: the role of VIVAPAROUS ABI3-LIKE (VAL) repressors.Journal of plant research · 2026Review
- cis- and trans-elements for the transcriptional regulation of sugar responsive genes: from current knowledge to future applications.Plant molecular biology · 2025Review
- B3 Superfamily in Cucumber (International journal of molecular sciences · 2025Article
- Characterization and expression analysis of the B3 gene family during seed development in Akebia trifoliata.BMC genomics · 2024Article
- ACRE, a class of AP2/ERF transcription factors, activates the expression of sweet potato ß-amylase and sporamin genes through the sugar-responsible element CMSRE-1.Plant molecular biology · 2024Article
- Identification and expression analyses of B3 genes reveal lineage-specific evolution and potential roles of REM genes in pepper.BMC plant biology · 2024Article
- Involvement of Abscisic Acid in Transition of Pea (Plants (Basel, Switzerland) · 2024Article
- Article
- Genome-wide identification and expression profiling of B3 transcription factor genes inFrontiers in plant science · 2023Article
- Interaction Analysis between theInternational journal of molecular sciences · 2022Article
- Genome-wide analysis of the B3 transcription factors reveals that RcABI3/VP1 subfamily plays important roles in seed development and oil storage in castor bean (Plant diversity · 2022Article
- Transition from Seeds to Seedlings: Hormonal and Epigenetic Aspects.Plants (Basel, Switzerland) · 2021Review
- Article
- Differential expression of SlKLUH controlling fruit and seed weight is associated with changes in lipid metabolism and photosynthesis-related genes.Journal of experimental botany · 2021Article
- Article
- The transcriptional repressors VAL1 and VAL2 recruit PRC2 for genome-wide Polycomb silencing in Arabidopsis.Nucleic acids research · 2021Article
- Ectopic Expression of the Transcriptional RegulatorThe Plant cell · 2020Article
- HSI2/VAL1 and HSL1/VAL2 function redundantly to repress DOG1 expression in Arabidopsis seeds and seedlings.The New phytologist · 2020Article
- Evidence that ERF transcriptional regulators serve as possible key molecules for natural variation in defense against herbivores in tall goldenrod.Scientific reports · 2020Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A recessive mutation hsi2 of Arabidopsis (Arabidopsis thaliana) expressing luciferase (LUC) under control of a short promoter derived from a sweet potato (Ipomoea batatas) sporamin gene (Spo(min)LUC) caused enhanced LUC expression under both low- and high-sugar conditions, which was not due to increased level of abscisic acid. The hsi2 mutant contained a nonsense mutation in a gene encoding a protein with B3 DNA-binding domain. HSI2 and two other Arabidopsis proteins appear to constitute a novel subfamily of B3 domain proteins distinct from ABI3, FUS3, and LEC2, which are transcription activators involved in seed development. The C-terminal part of HSI2 subfamily proteins contained a sequence similar to the ERF-associated amphiphilic repression (EAR) motif. Deletion of the C-terminal portion of HSI2 lost in the hsi2 mutant caused reduced nuclear targeting of HSI2. Null allele of HSI2 showed even higher Spo(min)LUC expression than the hsi2 mutant, whereas overexpression of HSI2 reduced the LUC expression. Transient coexpression of 35SHSI2 with Spo(min)LUC in protoplasts repressed the expression of LUC activity, and deletion or mutation of the EAR motif significantly reduced the repression activity of HSI2. These results indicate that HSI2 and related proteins are B3 domain-EAR motif active transcription repressors.
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