Trial reportPediatric nephrology (Berlin, Germany)2005
Premedication during micturating cystourethrogram to achieve sedation and anxiolysis.
Trial report in Pediatric nephrology (Berlin, Germany), 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 4 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Drugs for Procedural Sedation and Analgesia in Children: A Systematic Review and Meta-analysis.Drugs in R&D · 2025Pooled it
- Midazolam for sedation before procedures in adults and children: a systematic review update.Systematic reviews · 2021Pooled it
- Midazolam for sedation before procedures.The Cochrane database of systematic reviews · 2016Pooled it
- Urodynamic studies for management of urinary incontinence in children and adults.The Cochrane database of systematic reviews · 2013Pooled it
- Intranasal fentanyl versus placebo for pain in children during catheterization for voiding cystourethrography.Pediatric radiology · 2010Trial
- Use of sedative drugs at reducing the side effects of voiding cystourethrography in children.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2017Review
- Utility of sedation for young children undergoing dimercaptosuccinic acid renal scans.Pediatric radiology · 2016Article
- Evaluation of the effects of sedation administered via three different routes on the procedure, child and parent satisfaction during cystometry.SpringerPlus · 2016Article
- Anxiety in children undergoing VCUG: sedation or no sedation?Advances in urology · 2008Article
- Sedation with nitrous oxide compared with no sedation during catheterization for urologic imaging in children.Pediatric radiology · 2007Article
- Non-Intravenous Sedatives and Analgesics for Procedural Sedation for Imaging Procedures in Pediatric Patients.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAGReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Micturating cystourethrogram (MCUG) is an imaging technique indicated in the diagnosis and follow-up of many diseases. We investigated the reliability and the efficacy of midazolam and chloral hydrate in sedation and anxiolysis during micturating cystourethrogram. Fifty-three children of similar ages (39 girls, 14 boys, mean age of 5.8+/-3.5 years) were randomized to midazolam (n=17), chloral hydrate (n=18) and control groups (n=18). Oral midazolam 0.6 mg/kg or chloral hydrate 25 mg/kg or saline were administered to the study groups 15-30 min prior to the urinary catheterization. Brietkopf and Buttner, Frankl and Houpt scales and Spielberger's State Anxiety Inventory and parent's impressions were used to assess the level of sedation and anxiety. The Brietkopf and Buttner classification of emotional status and Houpt behavior rating scale demonstrated a significantly better emotional status and sedation in the midazolam group when compared to controls (P=0.01 and P=0.018, respectively). The catheterization was described as a more unpleasant and distressing event by the parents of the control and the chloral hydrate groups when compared to the parents of the midazolam group (P<0.05). Bladder capacity and frequency of detection of residual urine were not statistically different between the three study groups (P>0.05). Vital signs did not change significantly in any child. Sedation with midazolam does not have adverse effects on the results of micturating cystourethrogram, while it reduces the discomfort in children undergoing this radiological technique.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.