ArticleNucleic acids research2005
The recent transfer of a homing endonuclease gene.
Article in Nucleic acids research, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Telomere-to-telomere characterization of rDNA chromosome in the myxomycete Didymium iridis.BMC molecular and cell biology · 2026Article
- Mobile group I introns at nuclear rDNA position L2066 harbor sense and antisense homing endonuclease genes intervened by spliceosomal introns.Mobile DNA · 2022Article
- Article
- Horizontally-acquired genetic elements in the mitochondrial genome of a centrohelid Marophrys sp. SRT127.Scientific reports · 2019Article
- Accumulation of Stable Full-Length Circular Group I Intron RNAs during Heat-Shock.Molecules (Basel, Switzerland) · 2016Article
- Evolution of group II introns.Mobile DNA · 2015Article
- Phylogenetic analysis of LSU and SSU rDNA group I introns of lichen photobionts associated with the generaJournal of phycology · 2013Article
- Nuclear group I introns in self-splicing and beyond.Mobile DNA · 2013Article
- Evolution of small putative group I introns in the SSU rRNA gene locus of Phialophora species.BMC research notes · 2011Article
- Evolutionary dynamics of the mS952 intron: a novel mitochondrial group II intron encoding a LAGLIDADG homing endonuclease gene.Journal of molecular evolution · 2011Article
- Evolution of I-SceI homing endonucleases with increased DNA recognition site specificity.Journal of molecular biology · 2011Article
- A group II intron encodes a functional LAGLIDADG homing endonuclease and self-splices under moderate temperature and ionic conditions.RNA (New York, N.Y.) · 2010Article
- Homing endonucleases: from basics to therapeutic applications.Cellular and molecular life sciences : CMLS · 2010Review
- Group I introns and inteins: disparate origins but convergent parasitic strategies.Journal of bacteriology · 2009Review
- Evolution of Pleopsidium (lichenized Ascomycota) S943 group I introns and the phylogeography of an intron-encoded putative homing endonuclease.Journal of molecular evolution · 2007Article
- Short-term sequence evolution and vertical inheritance of the Naegleria twin-ribozyme group I intron.BMC evolutionary biology · 2006Article
- SegH and Hef: two novel homing endonucleases whose genes replace the mobC and mobE genes in several T4-related phages.Nucleic acids research · 2005Article
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6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The myxomycete Didymium iridis (isolate Panama 2) contains a mobile group I intron named Dir.S956-1 after position 956 in the nuclear small subunit (SSU) rRNA gene. The intron is efficiently spread through homing by the intron-encoded homing endonuclease I-DirI. Homing endonuclease genes (HEGs) usually spread with their associated introns as a unit, but infrequently also spread independent of introns (or inteins). Clear examples of HEG mobility are however sparse. Here, we provide evidence for the transfer of a HEG into a group I intron named Dir.S956-2 that is inserted into the SSU rDNA of the Costa Rica 8 isolate of D.iridis. Similarities between intron sequences that flank the HEG and rDNA sequences that flank the intron (the homing endonuclease recognition sequence) suggest that the HEG invaded the intron during the recent evolution in a homing-like event. Dir.S956-2 is inserted into the same SSU site as Dir.S956-1. Remarkably, the two group I introns encode distantly related splicing ribozymes with phylogenetically related HEGs inserted on the opposite strands of different peripheral loop regions. The HEGs are both interrupted by small spliceosomal introns that must be removed during RNA maturation.
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