ArticleJournal of molecular modeling2005
Structural and functional characterization of AtPTR3, a stress-induced peptide transporter of Arabidopsis.
Article in Journal of molecular modeling, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 47 citations in OpenAlex.
- Functional characterization of NRT1/PTR FAMILY transporters: looking for a needle in a haystack.The New phytologist · 2026Review
- Identification of QTLs for symbiotic nitrogen fixation and related traits in a soybean recombinant inbred line population.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Sugarcane Genotypes with Contrasting Biological Nitrogen Fixation Efficiencies Differentially Modulate Nitrogen Metabolism, Auxin Signaling, and Microorganism Perception Pathways.Plants (Basel, Switzerland) · 2022Article
- Genome-Wide Identification ofGenes · 2022Article
- Targeted designing functional markers revealed the role of retrotransposon derived miRNAs as mobile epigenetic regulators in adaptation responses of pistachio.Scientific reports · 2021Article
- Imbalanced Regulation of Fungal Nutrient Transports According to Phosphate Availability in a Symbiocosm Formed by Poplar, Sorghum, andFrontiers in plant science · 2019Article
- Mapping of novel salt tolerance QTL in an Excalibur × Kukri doubled haploid wheat population.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2018Article
- Genome-Wide Identification and Analysis of Apple NITRATE TRANSPORTER 1/PEPTIDE TRANSPORTER Family (NPF) Genes Reveals MdNPF6.5 Confers High Capacity for Nitrogen Uptake under Low-Nitrogen Conditions.International journal of molecular sciences · 2018Article
- Transcriptomic changes in Cucurbita pepo fruit after cold storage: differential response between two cultivars contrasting in chilling sensitivity.BMC genomics · 2018Article
- Article
- Comparative Leaf and Root Transcriptomic Analysis of two Rice Japonica Cultivars Reveals Major Differences in the Root Early Response to Osmotic Stress.Rice (New York, N.Y.) · 2016Article
- Evolutionary classification of ammonium, nitrate, and peptide transporters in land plants.BMC evolutionary biology · 2014Article
- A dipeptide transporter from the arbuscular mycorrhizal fungus Rhizophagus irregularis is upregulated in the intraradical phase.Frontiers in plant science · 2014Article
- In silico and in vivo studies of an Arabidopsis thaliana gene, ACR2, putatively involved in arsenic accumulation in plants.Journal of molecular modeling · 2012Article
- Genomic survey, characterization and expression profile analysis of the peptide transporter family in rice (Oryza sativa L.).BMC plant biology · 2010Article
- AtPTR1 and AtPTR5 transport dipeptides in planta.Plant physiology · 2008Article
- Nitrate efflux at the root plasma membrane: identification of an Arabidopsis excretion transporter.The Plant cell · 2007Article
- Improved drought tolerance without undesired side effects in transgenic plants producing trehalose.Plant molecular biology · 2007Article
- AtPTR3, a wound-induced peptide transporter needed for defence against virulent bacterial pathogens in Arabidopsis.Planta · 2007Article
- Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A T-DNA tagged mutant line of Arabidopsis thaliana, produced with a promoter trap vector carrying a promoterless gus (uidA) as a reporter gene, showed GUS induction in response to mechanical wounding. Cloning of the chromosomal DNA flanking the T-DNA revealed that the insert had caused a knockout mutation in a PTR-type peptide transporter gene named At5g46050 in GenBank, here renamed AtPTR3. The gene and the deduced protein were characterized by molecular modelling and bioinformatics. Molecular modelling of the protein with fold recognition identified 12 transmembrane spanning regions and a large loop between the sixth and seventh helices. The structure of AtPTR3 resembled the other PTR-type transporters of plants and transporters in the major facilitator superfamily. Computer analysis of the AtPTR3 promoter suggested its expression in roots, leaves and seeds, complex hormonal regulation and induction by abiotic and biotic stresses. The computer-based hypotheses were tested experimentally by exposing the mutant plants to amino acids and several stress treatments. The AtPTR3 gene was induced by the amino acids histidine, leucine and phenylalanine in cotyledons and lower leaves, whereas a strong induction was obtained in the whole plant upon exposure to salt. Furthermore, the germination frequency of the mutant line was reduced on salt-containing media, suggesting that the AtPTR3 protein is involved in stress tolerance in seeds during germination.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.