ReviewNaunyn-Schmiedeberg's archives of pharmacology2005
TRPC3: a versatile transducer molecule that serves integration and diversification of cellular signals.
Review in Naunyn-Schmiedeberg's archives of pharmacology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 24 citations in OpenAlex.
- Polymodal TRPC signaling: Emerging role in phenotype switching and tissue remodeling.Communicative & integrative biology · 2010Article
- TRPC3 regulates agonist-stimulated Ca2+ mobilization by mediating the interaction between type I inositol 1,4,5-trisphosphate receptor, RACK1, and Orai1.The Journal of biological chemistry · 2010Article
- Complex regulation of the TRPC3, 6 and 7 channel subfamily by diacylglycerol and phosphatidylinositol-4,5-bisphosphate.Cell calcium · 2008Article
- Transient receptor potential (TRP) channels as drug targets.Naunyn-Schmiedeberg's archives of pharmacology · 2006Article
- TRP channels as new pharmacological targets.Naunyn-Schmiedeberg's archives of pharmacology · 2005Article
- Functional characterization and physiological relevance of the TRPC3/6/7 subfamily of cation channels.Naunyn-Schmiedeberg's archives of pharmacology · 2005Review
- Regulation of TRPM2 channels in neutrophil granulocytes by ADP-ribose: a promising pharmacological target.Naunyn-Schmiedeberg's archives of pharmacology · 2005Review
- The TRPC2 ion channel and pheromone sensing in the accessory olfactory system.Naunyn-Schmiedeberg's archives of pharmacology · 2005Review
- Structure-function analysis of TRPV channels.Naunyn-Schmiedeberg's archives of pharmacology · 2005Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Transient receptor potential (TRP) proteins have been recognized as sensors for a wide variety of external and internal signals involved in maintenance of cellular homeostasis and control of physiological functions. Evidence of a striking versatility in terms of signal integration and transduction has been reported for members of the canonical (or classical) TRP subfamily (TRPCs). TRPC species are cation channel subunits and emerge as multifunctional signal transduction molecules that are able to function as components of divergent signalplexes. Results obtained in heterologous expression systems suggest TRPC3 as a paradigm of multifunctional signal transduction by a cation channel protein. TRPC3 serves cellular Ca(2+) signaling by multiple mechanisms and may control a variety of distinct physiological functions. In this review, we summarize current knowledge on the properties and possible signaling partners of TRPC3, and discuss the role of TRPC3 channel proteins in cellular signaling networks.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.