Evidence map›Paper›PMID 15888771›Full record

ArticleGut2005

The time to eradicate gastric cancer is now.

D Y Graham, A Shiotani

Open access · bronzeAbstract read
In one paragraph

Article in Gut, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
11.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 115 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Effect ofFrontiers in oncology · 2024
    Review
  5. Review
  6. Geographic Variability of Gastric Cancer Incidence in Kazakhstan.Asian Pacific journal of cancer prevention : APJCP · 2022
    Article
  7. Article
  8. Chemoprevention Against Gastric Cancer.Gastrointestinal endoscopy clinics of North America · 2021
    Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Epidemiology ofToxins · 2018
    Review
  14. Toward early detection of Helicobacter pylori-associated gastric cancer.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2018
    Article
  15. Helicobacter pylori as an oncogenic pathogen, revisited.Expert reviews in molecular medicine · 2017
    Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

D Y GrahamMichael E DeBakey Veterans Affairs Medical Center, RM 3A-320 (111D), 2002 Holcombe Boulevard, Houston, TX 77030, USA. dgraham@bcm.tmc.edu
A Shiotani
Michael E. DeBakey VA Medical Center · USWakayama University · JP

Funding

Tissue Analysis & Molecular Imaging CoreP30DK056338 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI Geoffrey A Preidis · 2001 to 2026
$28.3M
NIDDK NIH HHS DK56338NIDDK NIH HHS P30 DK056338
6 · The paper itself

Abstract

Worldwide gastric cancer remains one of the most common cancers, killing upwards of one million people each year. While the molecular pathogenesis remains unclear, infection with the bacterium Helicobacter pylori is considered a "necessary but not sufficient" cause, not surprisingly as gastric cancer has long been known to be associated with atrophic gastritis. Eradication of H pylori is expected to virtually eliminate gastric cancer and H pylori associated peptic ulcer within approximately 40 years and thus reduce overall mortality. In the USA, the incidence of gastric cancer in the general population is low, reflecting the change in the pattern of gastritis from atrophic to non-atrophic and in the low and decreasing prevalence of H pylori infection in the middle and upper classes. However, the plan for eradication of this important pathogen must be considered within the context of the prevalence and outcome within specific populations.

Indexed as

Helicobacter pyloriAdolescentAdultAgedAge DistributionChildChild, PreschoolCost-Benefit AnalysisHelicobacter InfectionsHumansInfantInfant, NewbornMass ScreeningMiddle AgedRisk FactorsStomach Neoplasms

Identifiers

PMID15888771
PMCPMC1774520
OpenAlexW2033381430

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.