Evidence map›Paper›PMID 15883751›Full record

ArticleCardiovascular drugs and therapy2005

Glucagon like peptide-1 is protective against myocardial ischemia/reperfusion injury when given either as a preconditioning mimetic or at reperfusion in an isolated rat heart model.

Amal K Bose, Mihaela M Mocanu, Richard D Carr, Derek M Yellon

2 registry-linked trialsAbstract read
PubMed Publisher
In one paragraph

Article in Cardiovascular drugs and therapy, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01761318 phase4completedstarted 2013, after this paper: background citation

Magnetic Resonance Assessment of Victoza Efficacy in the Regression of Cardiovascular Dysfunction In Type 2 Diabetes Mellitus

Ran2013Enrolled50Registered outcomes48Posted comparisons0ConditionsCardiovascular Disease, Diabetes Mellitus Type 2, Diastolic Dysfunction, Fatty LiverArmsliraglutide, Liraglutide - Placebo
PMID 16776751PMID 18819705PMID 19915017PMID 19349323PMID 19930006PMID 19805654PMID 15171747PMID 15313949PMID 15353407PMID 15582729PMID 15591516PMID 16123478other papers from this trial
Open the trial in the graph
NCT00256256 nacompletednot on this map

The Effect of GLP-1 on Glucose Uptake in the CNS and Heart in Healthy Subjects During Normoglycaemia Assessed by Positron Emission Tomografi

TypeinterventionalSponsorUniversity of AarhusRan2005 to 2007Enrolled10ConditionsType 2 Diabetes, Stroke, Myocardial InfarctionArmsglucagon-like-peptide-1
3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 125 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Amal K BoseThe Hatter Institute and Centre for Cardiology, University College London Hospital & Medical School, London, UK.
Mihaela M Mocanu
Richard D Carr
Derek M Yellon
Royal London Hospital · GBNovo Nordisk (Denmark) · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Ischemic Preconditioning, MyocardialAnimalsCardiotonic AgentsGlucagonGlucagon-Like Peptide 1HumansIn Vitro TechniquesMaleMyocardial ReperfusionMyocardial Reperfusion InjuryPeptide FragmentsProtein PrecursorsRatsRats, Sprague-DawleyTime FactorsCardiotonic AgentsGlucagonGlucagon-Like Peptide 1Peptide FragmentsProtein Precursors

Identifiers

PMID15883751
OpenAlexW1968785372

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.