ArticleMycopathologia2005
Molecular subtyping of clinical isolates of Candida albicans and identification of Candida dubliniensis Malaysia.
Article in Mycopathologia, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Growth inhibition of Candida species by Wickerhamomyces anomalus mycocin and a lactone compound of Aureobasidium pullulans.BMC complementary and alternative medicine · 2014Article
- Issues in identifying germ tube positive yeasts by conventional methods.Journal of clinical laboratory analysis · 2014Article
- Candida dubliniensis: an appraisal of its clinical significance as a bloodstream pathogen.PloS one · 2012Article
- Candida dubliniensis: epidemiology and phenotypic methods for identification.Mycopathologia · 2010Review
- Molecular analysis of Candida albicans isolates from clinical specimens.Mycopathologia · 2010Article
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Authors and funding
4 authors.
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Abstract
The genotypes of 221 recent isolates of Candida albicans from various clinical specimens of 213 patients admitted to the University Malaya Medical Centre, Malaysia was determined based on the amplification of a transposable intron region in the 25 S rRNA gene. The analyses of 178 C. albicans isolated from nonsterile clinical specimens showed that they could be classified into three genotypes: genotype A (138 isolates), genotype B (38 isolates) and genotype C (2 isolates). The genotyping of 43 clinical isolates from sterile specimens showed that they belonged to genotype A (29 isolates), genotype B (10 isolates), genotype C (2 isolates) and genotype D (2 isolates). The overall distribution of C. albicans genotypes in sterile and nonsterile specimens appeared similar, with genotype A being the most predominant type. This study reported the identification of C. dubliniensis (genotype D) in 2 HIV-negative patients with systemic candidiasis, which were missed by the routine mycological procedure. The study demonstrated the genetic diversity of clinical isolates of C. albicans in Malaysia.
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