ArticleCirculation2005
Clinical significance of statin pleiotropic effects: hypotheses versus evidence.
Article in Circulation, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT01770210 (A Multicenter, Open-label, 30-week Observational Clinical Study to Examine the Progress of Patients After Leaving the Cardiology Clinic or Unit Due to Acute Cardiovascular Event.), which is not on this map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Multicenter, Open-label, 30-week Observational Clinical Study to Examine the Progress of Patients After Leaving the Cardiology Clinic or Unit Due to Acute Cardiovascular Event.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effect of statin therapy on the progression of coronary atherosclerosis.BMC cardiovascular disorders · 2012Pooled it
- Impact of evolocumab on the pharmacodynamic profiles of clopidogrel in patients with atherosclerotic cardiovascular disease: a randomised, double-blind, placebo-controlled study.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2023Trial
- Pharmacodynamic effects of adjunctive high dose atorvastatin on double dose clopidogrel in patients with high on-treatment platelet reactivity depending on diabetes mellitus status.Journal of thrombosis and thrombolysis · 2014 · on this mapTrial
- Peripheral artery disease, biomarkers, and darapladib.American heart journal · 2011Trial
- Short-term statin treatment improves endothelial function and neurohormonal imbalance in normocholesterolaemic patients with non-ischaemic heart failure.Heart (British Cardiac Society) · 2006Trial
- Effect of Statin Lipophilicity on the Proliferation of Hepatocellular Carcinoma Cells.Biology · 2024Article
- Statins in Neuro-ophthalmology.Neuro-ophthalmology (Aeolus Press) · 2021Review
- Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles.Journal of visualized experiments : JoVE · 2017Article
- Effects of statin therapy on platelet reactivity after percutaneous coronary revascularization in patients with acute coronary syndrome.Journal of thrombosis and thrombolysis · 2017Observational
- Effect of pravastatin on endothelial dysfunction in children with medium to giant coronary aneurysms due to Kawasaki disease.World journal of pediatrics : WJP · 2014Article
- Cholesterol, C-Reactive Protein, and Periodontitis: HMG-CoA-Reductase Inhibitors (Statins) as Effect Modifiers.ISRN dentistry · 2011Article
- Recent advances in the management of chronic stable angina II. Anti-ischemic therapy, options for refractory angina, risk factor reduction, and revascularization.Vascular health and risk management · 2010Review
- Effect of hydroxymethylglutaryl coenzyme-a reductase inhibitors on the long-term progression of rheumatic mitral valve disease.Circulation · 2010Article
- Lp-PLA2: A new target for statin therapy.Current atherosclerosis reports · 2010Review
- Low-density lipoprotein cholesterol reduction and prevention of cardiovascular disease.Mayo Clinic proceedings · 2009Article
- Atherosclerosis as a disease of failed endogenous repair.Frontiers in bioscience : a journal and virtual library · 2008Review
- Review
- Rosuvastatin versus atorvastatin in achieving lipid goals in patients at high risk for cardiovascular disease in clinical practice: A randomized, open-label, parallel-group, multicenter study (DISCOVERY Alpha study).Current therapeutic research, clinical and experimental · 2006Article
- Insulin resistance and the endothelium.Current diabetes reports · 2005Review
Corrections and comments
- Comment on
- Erratum issued
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
15883224What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.