ArticleThe Journal of general physiology1992
Chemosensory responses in isolated olfactory receptor neurons from Necturus maculosus.
Article in The Journal of general physiology, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 80 citations in OpenAlex.
- Odor-evoked inhibition of olfactory sensory neurons drives olfactory perception in Drosophila.Nature communications · 2017Article
- Mechanisms underlying odorant-induced and spontaneous calcium signals in olfactory receptor neurons of spiny lobsters, Panulirus argus.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2014Article
- Specificities of olfactory receptor neuron responses to amino acids in the black bullhead catfish (Ameiurus melas).Pflugers Archiv : European journal of physiology · 2010Article
- Pulse stimulation with odors or IBMX/forskolin potentiates responses in isolated olfactory neurons.Chemical senses · 2006Article
- Tonic and phasic receptor neurons in the vertebrate olfactory epithelium.Biophysical journal · 2003Article
- Patch-clamp analysis of voltage-activated and chemically activated currents in the vomeronasal organ of Sternotherus odoratus (stinkpot/musk turtle).The Journal of experimental biology · 2001Article
- Neuromodulatory effects of gonadotropin releasing hormone on olfactory receptor neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2000Article
- Peripheral odor coding in the rat and frog: quality and intensity specification.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2000Article
- Adaptation of the odour-induced response in frog olfactory receptor cells.The Journal of physiology · 1999Article
- Kinetic models of odor transduction implemented as artificial neural networks. Simulations of complex response properties of honeybee olfactory neurons.Biological cybernetics · 1995Article
- Inhibition of taurine and 5'AMP olfactory receptor sites of the spiny lobster Panulirus argus by odorant compounds and mixtures.Journal of comparative physiology. A, Sensory, neural, and behavioral physiology · 1995Article
- Guanine nucleotides modulate steady-state inactivation of voltage-gated sodium channels in frog olfactory receptor neurons.The Journal of membrane biology · 1994Article
- Emerging complexity of odor transduction.Proceedings of the National Academy of Sciences of the United States of America · 1994Review
- Cyclic nucleotide- and inositol phosphate-gated ion channels in lobster olfactory receptor neurons.Proceedings of the National Academy of Sciences of the United States of America · 1994Article
- Evidence for a peripheral olfactory memory in imprinted salmon.Proceedings of the National Academy of Sciences of the United States of America · 1994Article
- Neurohormone D induces ionic current changes in cockroach central neurones.Journal of comparative physiology. A, Sensory, neural, and behavioral physiology · 1994Article
- Action potentials and chemosensitive conductances in the dendrites of olfactory neurons suggest new features for odor transduction.The Journal of general physiology · 1994Article
- Gating properties of the cAMP-gated channel in toad olfactory receptor cells.The Journal of physiology · 1993Article
- Modulation of Cl-, K+, and nonselective cation conductances by taurine in olfactory receptor neurons of the mudpuppy Necturus maculosus.The Journal of general physiology · 1993Article
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1 author at 1 institution in 1 country.
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Abstract
Olfactory receptor neurons were isolated without enzymes from the mudpuppy, Necturus maculosus, and tested for chemosensitivity. The cells responded to odorants with changes in firing frequency and alterations in excitability that were detected with tight-seal patch electrodes using on-cell and whole-cell recording conditions. Chemosensitive cells exhibited two primary response characteristics: excitation and inhibition. Both types of primary response were observed in different cells stimulated by mixtures of amino acids as well as by the single compound L-alanine, suggesting that there may be more than one transduction pathway for some odorants. Using the normal whole-cell recording method, the chemosensitivity of competent cells washed out rapidly; a resistive whole-cell method was used to record odorant responses under current-clamp conditions. In response to chemical stimulation, excitability appeared to be modulated in several different ways in different cells: odorants induced hyperpolarizing or depolarizing receptor potentials, elicited or inhibited transient, rhythmic generator potentials, and altered excitability without changing the membrane potential or input resistance. These effects suggest that olfactory transduction is mediated through at least three different pathways with effects on four or more components of the membrane conductance. Polychotomous pathways such as these may be important for odor discrimination and for sharpening the "odor image" generated in the olfactory epithelium.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.