ArticleNeuron2005
Long-term plasticity mediated by mGluR1 at a retinal reciprocal synapse.
Article in Neuron, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 32 citations in OpenAlex.
- Short-term plasticity and context-dependent circuit function: Insights from retinal circuitry.Science advances · 2024Review
- Glycine Release Is Potentiated by cAMP via EPAC2 and CaThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Retinoschisin Facilitates the Function of L-Type Voltage-Gated Calcium Channels.Frontiers in cellular neuroscience · 2017Article
- The Contribution of L-Type CaFrontiers in molecular neuroscience · 2017Article
- Type-1, but Not Type-5, Metabotropic Glutamate Receptors are Coupled to Polyphosphoinositide Hydrolysis in the Retina.Neurochemical research · 2016Article
- Proton-mediated block of Ca2+ channels during multivesicular release regulates short-term plasticity at an auditory hair cell synapse.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- Nitric oxide mediates activity-dependent plasticity of retinal bipolar cell output via S-nitrosylation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Article
- Glycine transporter 1 modulates GABA release from amacrine cells by controlling occupancy of coagonist binding site of NMDA receptors.Journal of neurophysiology · 2013Article
- Article
- "mGlu Receptors in the Retina" - WIREs Membrane Transport and Signaling.Wiley interdisciplinary reviews. Membrane transport and signaling · 2012Article
- Light-evoked lateral GABAergic inhibition at single bipolar cell synaptic terminals is driven by distinct retinal microcircuits.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2011Article
- Disruption of metabotropic glutamate receptor signalling is a major defect at cerebellar parallel fibre-Purkinje cell synapses in staggerer mutant mice.The Journal of physiology · 2011Article
- Interneuron circuits tune inhibition in retinal bipolar cells.Journal of neurophysiology · 2010Article
- Activation of the tonic GABAC receptor current in retinal bipolar cell terminals by nonvesicular GABA release.Journal of neurophysiology · 2009Article
- Retinal ON bipolar cells express a new PCP2 splice variant that accelerates the light response.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2008Article
- Short-term depression at the reciprocal synapses between a retinal bipolar cell terminal and amacrine cells.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2007Article
- The synaptic mechanism of direction selectivity in distal processes of starburst amacrine cells.Neuron · 2006Article
- Receptor and transmitter release properties set the time course of retinal inhibition.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2006Article
- GABA transporters regulate a standing GABAC receptor-mediated current at a retinal presynaptic terminal.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2006Article
- GABA(A), GABA(C) and glycine receptor-mediated inhibition differentially affects light-evoked signalling from mouse retinal rod bipolar cells.The Journal of physiology · 2006Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
The flow of information across the retina is controlled by reciprocal synapses between bipolar cell terminals and amacrine cells. However, the synaptic delays and properties of plasticity at these synapses are not known. Here we report that glutamate release from goldfish Mb-type bipolar cell terminals can trigger fast (delay of 2-3 ms) and transient GABA(A) IPSCs and a much slower and more sustained GABA(C) feedback. Synaptically released glutamate activated mGluR1 receptors on amacrine cells and, depending on the strength of presynaptic activity, potentiated subsequent feedback. This poststimulus enhancement of GABAergic feedback lasted for up to 10 min. This form of mGluR1-mediated long-term synaptic plasticity may provide retinal reciprocal synapses with adaptive capabilities.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.