ArticleThe Journal of comparative neurology2005
Collagen XVII and BPAG1 expression in the retina: evidence for an anchoring complex in the central nervous system.
Article in The Journal of comparative neurology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 68 citations in OpenAlex.
- Betz cells of the primary motor cortex.The Journal of comparative neurology · 2024Review
- Extracellular Matrix: The Unexplored Aspects of Retinal Pathologies and Regeneration.Advances in experimental medicine and biology · 2023Review
- Case report: Bullous pemphigoid arising in a patient with scleroderma and multiple sclerosis.Frontiers in medicine · 2022Article
- Type XVII collagen: Relevance of distinct epitopes, complement-independent effects, and association with neurological disorders in pemphigoid disorders.Frontiers in immunology · 2022Review
- BP180/Collagen XVII: A Molecular View.International journal of molecular sciences · 2021Review
- Biological predictors shared by dementia and bullous pemphigoid patients point out a cross-antigenicity between BP180/BP230 brain and skin isoforms.Immunologic research · 2018Article
- Autoimmune Subepidermal Bullous Diseases of the Skin and Mucosae: Clinical Features, Diagnosis, and Management.Clinical reviews in allergy & immunology · 2018Review
- Subepidermal autoimmune bullous diseases: overview, epidemiology, and associations.Immunologic research · 2018Review
- The Growing Incidence of Bullous Pemphigoid: Overview and Potential Explanations.Frontiers in medicine · 2018Review
- Neurodegenerative disorders, bullous pemphigoid and psoriasis: a comparative study in ethnic Poles indicates that Parkinson's disease is more relevant to bullous pemphigoid.Postepy dermatologii i alergologii · 2017Article
- Region- and Cell-Specific Expression of Transmembrane Collagens in Mouse Brain.Frontiers in integrative neuroscience · 2017Article
- Psychiatric and neurological disorders are associated with bullous pemphigoid - a nationwide Finnish Care Register study.Scientific reports · 2016Article
- A population-based study of the association between bullous pemphigoid and neurologic disorders.Journal of the American Academy of Dermatology · 2014Article
- Collagen XVII: a shared antigen in neurodermatological interactions?Clinical & developmental immunology · 2013Review
- The dynamic architecture of photoreceptor ribbon synapses: cytoskeletal, extracellular matrix, and intramembrane proteins.Visual neuroscience · 2011Review
- Collagen XIX is expressed by interneurons and contributes to the formation of hippocampal synapses.The Journal of comparative neurology · 2010Article
- Human retinal Müller cells synthesize collagens of the vitreous and vitreoretinal interface in vitro.Molecular vision · 2008Article
- Nok plays an essential role in maintaining the integrity of the outer nuclear layer in the zebrafish retina.Experimental eye research · 2006Article
- Laminin deficits induce alterations in the development of dopaminergic neurons in the mouse retina.Visual neuroscienceArticle
- Extracellular Matrix Components Regulate Cellular Polarity and Tissue Structure in the Developing and Mature Retina.Journal of ophthalmic & vision researchReview
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 3 countries.
Funding
Abstract
The ectoderm gives rise not only to the skin but also to the entire CNS. This common embryonic lineage suggests that some molecular isoforms might serve analogous functions in both tissues. Indeed, not only are laminins important components of dermal adhesion mechanisms, but they also regulate some aspects of synaptic development in both the CNS and the PNS. In the skin, laminins are part of a hemidesmosome complex essential for basal keratinocyte adhesion that includes collagen XVII (BP180) and BPAG1 (dystonin/BP230). Here, we show that CNS neurons also express collagen XVII and BPAG1 and that these molecules are expressed in the adult and developing retina. In the retina, isoforms of collagen XVII and BPAG1 are colocalized with laminins at photoreceptor synapses and around photoreceptor outer segments; both molecules are expressed by rods, whereas cones express collagen XVII but not BPAG1. Moreover, biochemical data demonstrate that collagen XVII complexes with retinal laminins. We propose that collagen XVII and BPAG1 isoforms may help to anchor elements of the rod photoreceptor cytomatrix to the extracellular matrix.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.