Evidence map›Paper›PMID 15879620›Full record

ReviewClinical reviews in allergy & immunology2005

Extrahepatic manifestations of cholestatic liver diseases: pathogenesis and therapy.

Thomas Pusl, Ulrich Beuers

Abstract readReview
PubMed Publisher
In one paragraph

Review in Clinical reviews in allergy & immunology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Cholestatic pruritus: Emerging mechanisms and therapeutics.Journal of the American Academy of Dermatology · 2019
    Pooled it
  2. Article
  3. Article
  4. [Progress in diagnosis and therapy of extrahepatic manifestations of cholestatic liver diseases].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2016
    Article
  5. Hepatic osteodystrophy.Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases · 2014
    Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Cholestasis and metabolic bone disease - a clinical review.Wiener medizinische Wochenschrift (1946) · 2008
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Thomas PuslDepartment of Medicine II, Klinikum of the University of Munich-Grosshadern, Munich, Germany.
Ulrich Beuers

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pruritus, fatigue, and metabolic bone disease are frequent complications of cholestatic liver diseases, which can be quite distressing for the patient and can considerably reduce the quality of life. The molecular pathogenesis of these extrahepatic manifestations of cholestasis is poorly understood, and hypotheses to explain these symptoms are being discussed. This article provides treatment recommendations for the complications of cholestasis based on putative pathomechanisms and summarizes recent experimental and clinical data involving management options.

Indexed as

Bone Diseases, MetabolicCholangitis, SclerosingCholestasisFatigueHumansPruritus

Identifiers

PMID15879620

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.