ReviewPostgraduate medical journal2005
Multiple sclerosis: diagnosis and the management of acute relapses.
Review in Postgraduate medical journal, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02490046 (Single Centre Open-label Feasibility Study Evaluating the Use of D-mannose in Multiple Sclerosis), which is not on this map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Single Centre Open-label Feasibility Study Evaluating the Use of D-mannose in Multiple Sclerosis
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Children and adolescents adjustment to parental multiple sclerosis: a systematic review.BMC neurology · 2014Pooled it
- Comparative effects of pilates-based interventions on functional mobility, balance, fatigue, and quality of life in people with multiple sclerosis: a systematic review and network meta-analysis.BMC sports science, medicine & rehabilitation · 2026Article
- Multiple Sclerosis: Pathogenesis Mechanism and Biomarkers.Central nervous system agents in medicinal chemistry · 2025Review
- Multiple Sclerosis-A Demyelinating Disorder and Its Dental Considerations-A Literature Review with Own Case Report.Brain sciences · 2023Review
- Radiofrequency Ablation of Gasserian Ganglion in Trigeminal Neuralgia With Multiple Sclerosis: A Rare Clinical Case.Cureus · 2022Article
- Characterizing the time course of cerebrovascular reactivity in multiple sclerosis.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2022Article
- Pinocembrin Promotes OPC Differentiation and Remyelination via the mTOR Signaling Pathway.Neuroscience bulletin · 2021Article
- Current Utilization and Research Status of Traditional East Asian Herbal Medicine Treatment for Multiple Sclerosis: A Scoping Review.Frontiers in neurology · 2021Article
- Dietary Inflammatory Index and clinical course of multiple sclerosis.European journal of clinical nutrition · 2019Article
- Treatment of multiple sclerosis relapses with high-dose methylprednisolone reduces the evolution of contrast-enhancing lesions into persistent black holes.Journal of neurology · 2018Article
- Article
- Article
- Early recognition of multiple sclerosis using natural language processing of the electronic health record.BMC medical informatics and decision making · 2017Article
- Examining the effects of comorbidities on disease-modifying therapy use in multiple sclerosis.Neurology · 2016Observational
- How to run a multiple sclerosis relapse clinic.Practical neurology · 2016Article
- Multiple sclerosis following a spinal cord injury: a rare and unfortunate case.Spinal cord series and cases · 2016Article
- Symptomatic management in multiple sclerosis.Annals of Indian Academy of Neurology · 2015Review
- Beta-interferon exposure and onset of secondary progressive multiple sclerosis.European journal of neurology · 2015Article
- Dietary habits and selenium, glutathione peroxidase and total antioxidant status in the serum of patients with relapsing-remitting multiple sclerosis.Nutrition journal · 2014Article
- Retrospective US database analysis of persistence with glatiramer acetate vs. available disease-modifying therapies for multiple sclerosis: 2001-2010.BMC neurology · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Multiple sclerosis is an inflammatory demyelinating disease of the central nervous system that may result in a wide range of neurological symptoms and accumulating disability. Its course is unpredictable resulting in a changing pattern of clinical need. Diagnostic criteria for multiple sclerosis require objective evidence for dissemination in space and time. The diagnostic and management process should follow good practice guidelines with the person at the centre of the process. Appropriate support and information should be available from the time of diagnosis. Continuing education is key in enabling the person to actively participate in their management. In the event of an acute relapse the person should have direct access to the most appropriate local service. Provided medical causes have been excluded, corticosteroid treatment to hasten the recovery from the relapse should be considered. Management of an acute relapse should be comprehensive addressing any medical, functional, or psychosocial sequelae.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.