Trial reportJournal of the American Geriatrics Society2005
Effects of behavioral and drug therapy on nocturia in older incontinent women.
Trial report in Journal of the American Geriatrics Society, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 4 syntheses or guidelines pooled it, 101 citations in OpenAlex.
- Bladder training for treating overactive bladder in adults.The Cochrane database of systematic reviews · 2023Pooled it
- Efficacy and safety of desmopressin in women with nocturia: a systematic review and meta-analysis of randomized controlled trials.International urology and nephrology · 2019Pooled it
- Bladder training for urinary incontinence in adults.The Cochrane database of systematic reviews · 2004Pooled it
- Habit retraining for the management of urinary incontinence in adults.The Cochrane database of systematic reviews · 2004Pooled it
- The Comparison of Individual and Group Hybrid Telerehabilitation Methods in Women with Urinary Incontinence.International urogynecology journal · 2024Trial
- Effectiveness of Combined Behavioral and Drug Therapy for Overactive Bladder Symptoms in Men: A Randomized Clinical Trial.JAMA internal medicine · 2020Trial
- The effects of drug and behavior therapy on urgency and voiding frequency.International urogynecology journal · 2010Trial
- Nocturia, nocturnal incontinence prevalence, and response to anticholinergic and behavioral therapy.International urogynecology journal and pelvic floor dysfunction · 2008Trial
- Nocturnal polyuria and nocturia relief in patients treated with solifenacin for overactive bladder symptoms.International urogynecology journal and pelvic floor dysfunction · 2007Trial
- Canadian Urological Association best practice report: Diagnosis and management of nocturia.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2022Article
- Managing Nocturia in Frail Older Adults.Drugs & aging · 2021Review
- Development of an online personalized self-management intervention for men with uncomplicated LUTS.Neurourology and urodynamics · 2019Article
- Economic Burden of Illness in Adult Patients with Nocturia.Journal of managed care & specialty pharmacy · 2019Article
- Nocturia and associated mortality: observational data from the REDUCE trial.Prostate cancer and prostatic diseases · 2019Article
- Nocturia: aetiology and treatment in adults.Nature reviews. Urology · 2016Review
- Management of nocturia in the female.Current urology reports · 2015Review
- Medication adherence in the management of nocturia: challenges and solutions.Patient preference and adherence · 2015Review
- Nocturia reported in nightly sleep diaries: common occurrence with significant implications?Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2014Article
- Cataloging nocturia (circa 2014).Sleep · 2014Article
- Maintenance of the therapeutic effect of two high-dosage antimuscarinics in the management of overactive bladder in elderly women.International neurourology journal · 2013Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
objectivesTo examine changes in nocturia from a multicomponent behavioral training program or drug therapy in older women with urge or mixed (urge-predominant) urinary incontinence.
designA secondary analysis of data from a prospective, randomized clinical trial.
settingParent trial was an outpatient research protocol in Alabama.
participantsOne hundred ninety-seven women (aged 55-92) with incontinence and urodynamic evidence of bladder dysfunction. At baseline, 131 women (66% of participants) had nocturia.
interventionIn the parent study, participants received behavioral training, including four sessions of biofeedback-assisted pelvic floor muscle exercises, drug treatment (oxybutynin IR titrated from 2.5 mg per day to 5.0 mg three times a day), or placebo. MEASUREMENTS: Participant-completed bladder diaries were used to calculate changes in nocturia.
resultsBehavioral training reduced nocturia by a median 0.50 episodes per night and was significantly more effective than drug treatment (median reduction=0.30 episodes; P=.02) and placebo (median reduction=0.00 episodes; P<.001). Also, drug treatment was more effective than control (P=.007).
conclusionBoth behavioral training and drug treatment reduced nocturia more than placebo, but behavioral training was the most effective.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.