Evidence map›Paper›PMID 15875227›Full record

ArticleThe European journal of health economics : HEPAC : health economics in prevention and care2005

Influenza treatment with neuraminidase inhibitors: cost-effectiveness and cost-utility in healthy adults in the United Kingdom.

Beate Sander, Marlene Gyldmark, Frederick G Hayden, James Morris, Elvira Mueller, Rito Bergemann

Abstract read
In one paragraph

Article in The European journal of health economics : HEPAC : health economics in prevention and care, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Cost-effectiveness of adding oseltamivir to primary care for influenza-like-illness: economic evaluation alongside the randomised controlled ALICThe European journal of health economics : HEPAC : health economics in prevention and care · 2023
    Article
  2. Review
  3. A comparison of average wages with age-specific wages for assessing indirect productivity losses: analytic simplicity versus analytic precision.The European journal of health economics : HEPAC : health economics in prevention and care · 2017
    Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Beate SanderInstitute for Medical Outcome Research GmbH, Lörrach, Germany. bsander@uhnres.utoronto.ca
Marlene Gyldmark
Frederick G Hayden
James Morris
Elvira Mueller
Rito Bergemann

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We assessed the cost-effectiveness and cost-utility of treating influenza with neuraminidase inhibitors (oseltamivir and zanamivir) from a health care payer's and societal perspective in the United Kingdom. A simulation model was developed to predict morbidity and mortality due to influenza and its specified complications, comparing neuraminidase inhibitors with usual care in an otherwise healthy adult population. Robustness of the results was tested by one-way and multiway as well as probabilistic sensitivity analyses. Treatment with either neuraminidase inhibitor results in reduced morbidity and faster return to normal activities. However, oseltamivir dominates zanamivir in cost-utility analysis due to its lower costs. Comparing oseltamivir with usual care, the costs are pound14.36 per day of normal activity gained and pound5,600 per quality-adjusted life-year gained from the healthcare payer perspective. Oseltamivir dominates usual care from the societal perspective. Treatment with oseltamivir is a cost-effective strategy for otherwise healthy adults in the UK from both the healthcare payer and societal perspective.

Indexed as

Cost-Benefit AnalysisAcetamidesAdolescentAdultAntiviral AgentsDecision Support TechniquesEnzyme InhibitorsGuanidinesHumansInfluenza, HumanMiddle AgedNeuraminidaseOseltamivirPyransSialic AcidsUnited KingdomAcetamidesAntiviral AgentsEnzyme InhibitorsGuanidinesNeuraminidaseOseltamivirPyransSialic AcidsZanamivir

Identifiers

PMID15875227
PMCPMC7087894

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.