ArticleJournal of clinical microbiology2005
Identification of non-Helicobacter pylori spiral organisms in gastric samples from humans, dogs, and cats.
Article in Journal of clinical microbiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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Who cites it
46 citing papers in PubMed, 155 citations in OpenAlex.
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- [Detection of Helicobacter species in humans and their dog]Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina) · 2023Article
- Draft Genome Sequence ofMicrobiology resource announcements · 2022Article
- Gastric Helicobacter species associated with dogs, cats and pigs: significance for public and animal health.Veterinary research · 2022Review
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- An exploratory study on the presence of Helicobacter heilmannii and Helicobacter billis in the feces of companion dogs.Veterinary medicine and science · 2022Article
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- Genomic analysis of Helicobacter himalayensis sp. nov. isolated from Marmota himalayana.BMC genomics · 2020Article
- Prevalence of non Helicobacter pylori gastric Helicobacters in Iranian dyspeptic patients.BMC gastroenterology · 2020Article
- Helicobacter suis infection alters glycosylation and decreases the pathogen growth inhibiting effect and binding avidity of gastric mucins.Mucosal immunology · 2019Article
- Helicobacter infection in the hepatobiliary system and hepatic lesions: a possible association in dogs.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2019Article
- Helicobacter suis binding to carbohydrates on human and porcine gastric mucins and glycolipids occurs via two modes.Virulence · 2018Article
- The Resolution of Helicobacter suis-associated Gastric Lesions after Eradication Therapy.Internal medicine (Tokyo, Japan) · 2018Article
- Evidence for a primate origin of zoonotic Helicobacter suis colonizing domesticated pigs.The ISME journal · 2018Article
- Phylogeographic diversity and mosaicism of theMobile DNA · 2018Article
- Helicobacter pylori-induced gastric pathology: insights from in vivo and ex vivo models.Disease models & mechanisms · 2017Review
- Helical and rod-shaped bacteria swim in helical trajectories with little additional propulsion from helical shape.Science advances · 2016Article
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tightly coiled bacteria are a rare cause of gastric pathology in humans and represent a mixture of species for which a zoonotic origin is suspected. Similar organisms are common inhabitants of the gastric mucosae of carnivores and pigs. It was the goal of the present study to determine the actual occurrence of each individual Helicobacter species in human, canine, and feline stomachs in order to better understand the possible zoonotic significance. Gastric biopsy samples from humans with histological evidence of non-Helicobacter pylori spiral bacteria (n = 123) and samples from the gastric antrum, corpus, and cardia from dogs (n = 110) and cats (n = 43) were subjected to a multiplex PCR, enabling the identification of Helicobacter felis, Helicobacter bizzozeronii, Helicobacter salomonis, and "Candidatus Helicobacter suis." A PCR for detecting H. pylori was applied to all human samples. Single infections with "Candidatus Helicobacter suis," H. felis, H. bizzozeronii, H. salomonis, a hitherto unknown genotype of a non-H. pylori spiral organism (Helicobacter-like organism 135 [HLO135]), and H. pylori were identified in 30.9%, 8.9%, 2.4%, 11.4%, 7.3%, and 8.9% of the human biopsy samples, respectively. Mixed infections (16.3%) with two or even three of these were also found. In the canine stomach, H. bizzozeronii (70.0%) was encountered as the main spiral organism, while H. felis (62.7%) and HLO135 (67.4%) were the predominant Helicobacter species found in the feline gastric mucosa. Although the majority of human non-H. pylori organisms are Helicobacter species naturally occurring in the stomachs of pigs, cats, and dogs, the frequent identification of H. salomonis in human gastric biopsy samples is in contrast to its rare identification in pet carnivore samples, urging us to suspect other sources of infection.
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