ArticleApplied and environmental microbiology2005
Genetically engineered wine yeast produces a high concentration of L-lactic acid of extremely high optical purity.
Article in Applied and environmental microbiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- Comparative analysis of heterologous lactate dehydrogenase expression in Ogataea polymorpha for enhanced L-Lactic acid production.Journal of biological engineering · 2026Article
- Synthetic biology strategies for sustainable bioplastic production by yeasts.Journal of microbiology (Seoul, Korea) · 2025Review
- Native and Recombinant Yeast Producers of Lactic Acid: Characteristics and Perspectives.International journal of molecular sciences · 2025Review
- Global trends and future prospects of lactic acid production from lignocellulosic biomass.RSC advances · 2023Article
- Harnessing originally robust yeast for rapid lactic acid bioproduction without detoxification and neutralization.Scientific reports · 2022Article
- Recent Advances in Lactic Acid Production by Lactic Acid Bacteria.Applied biochemistry and biotechnology · 2021Review
- l-Lactic Acid Production Using EngineeredJournal of fungi (Basel, Switzerland) · 2021Article
- Mechanisms underlying lactic acid tolerance and its influence on lactic acid production inMicrobial cell (Graz, Austria) · 2021Review
- Lactic acid production - producing microorganisms and substrates sources-state of art.Heliyon · 2020Review
- Technological Microbiology: Development and Applications.Frontiers in microbiology · 2017Review
- Environmentally Friendly Production of D(-) Lactic Acid byInternational journal of microbiology · 2017Article
- Improvement of lactic acid production in Saccharomyces cerevisiae by a deletion of ssb1.Journal of industrial microbiology & biotechnology · 2016Article
- Hydrophilic compounds in liquids of enzymatic hydrolyzed spruce and pine biomass.Data in brief · 2015Article
- L-lactic acid production by Aspergillus brasiliensis overexpressing the heterologous ldha gene from Rhizopus oryzae.Microbial cell factories · 2015Article
- Article
- Expression of Lactate Dehydrogenase in Aspergillus niger for L-Lactic Acid Production.PloS one · 2015Article
- Nuclear localization of Haa1, which is linked to its phosphorylation status, mediates lactic acid tolerance in Saccharomyces cerevisiae.Applied and environmental microbiology · 2014Article
- Production of L-lactic acid by the yeast Candida sonorensis expressing heterologous bacterial and fungal lactate dehydrogenases.Microbial cell factories · 2013Article
- Bio-based production of organic acids with Corynebacterium glutamicum.Microbial biotechnology · 2013Review
- Quinone-dependent D-lactate dehydrogenase Dld (Cg1027) is essential for growth of Corynebacterium glutamicum on D-lactate.BMC microbiology · 2010Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
For mass production of lactic acid, we newly constructed a transgenic wine yeast strain that included six copies of the bovine L-lactate dehydrogenase gene on the genome. On fermentation in inexpensive cane juice-based medium, L-lactate production of this recombinant reached 122 g/liter and the optical purity was 99.9% or higher.
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Registered trials
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